Related references
Note: Only part of the references are listed.Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy results from a randomised, double-blind, placebo-controlled, phase 3 trial
Peter Schmid et al.
LANCET ONCOLOGY (2020)
Know your enemy: Genetics, aging, exposomic and inflammation in the war against triple negative breast cancer
Francesco Fabbri et al.
SEMINARS IN CANCER BIOLOGY (2020)
The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer
Andrea J. Luker et al.
BMC IMMUNOLOGY (2020)
A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer
Amit M. Oza et al.
CLINICAL CANCER RESEARCH (2020)
ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer
Saioa Mendaza et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer
Shaoquan Zheng et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
AID assists DNMT1 to attenuate BCL6 expression through DNA methylation in diffuse large B-cell lymphoma cell lines
Junna Jiao et al.
NEOPLASIA (2020)
Triple-Negative Breast Cancer: A Review of Conventional and Advanced Therapeutic Strategies
Mauricio A. Medina et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)
Low-dose decitabine enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by re-modulating the tumor microenvironment
Ganjun Yu et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2019)
Dnmt1 links BCR-ABLp210 to epigenetic tumor stem cell priming in myeloid leukemia
Carolina Vicente-Duenas et al.
LEUKEMIA (2019)
Advances in the use of PARP inhibitors for BRCA1/2-associated breast cancer: talazoparib
Kelly E. McCann
FUTURE ONCOLOGY (2019)
Expression and clinicopathological significance of DNA methyltransferase 1, 3A and 3B in tamoxifen-treated breast cancer patients
Rosa Jahangiri et al.
GENE (2019)
A phase II study of guadecitabine in higher-risk myelodysplastic syndrome and low blast count acute myeloid leukemia after azacitidine failure
Marie Sebert et al.
HAEMATOLOGICA (2019)
Long noncoding RNA DDX11-AS1 epigenetically represses LATS2 by interacting with EZH2 and DNMT1 in hepatocellular carcinoma
Yong Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Strobilanthes crispus inhibits migration, invasion and metastasis in breast cancer
Yusha'u Shuaibu Baraya et al.
JOURNAL OF ETHNOPHARMACOLOGY (2019)
GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
Zefang Tang et al.
NUCLEIC ACIDS RESEARCH (2019)
The Anticancer and Antioxidant Effects of Muscadine Grape Extracts on Racially Different Triple-negative Breast Cancer Cells
Patricia Mendonca et al.
ANTICANCER RESEARCH (2019)
Epigenetic silencing of genes enhanced by collective role of reactive oxygen species and MAPK signaling downstream ERK/Snail axis: Ectopic application of hydrogen peroxide repress CDH1 gene by enhanced DNA methyltransferase activity in human breast cancer
Nibedita Pradhan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)
Guadecitabine in myelodysplastic syndromes: promising but there is still progress to be made
Lionel Ades et al.
LANCET HAEMATOLOGY (2019)
Guadecitabine (SGI-110) in patients with intermediate or high-risk myelodysplastic syndromes: phase 2 results from a multicentre, open-label, randomised, phase 1/2 trial
Guillermo Garcia-Manero et al.
LANCET HAEMATOLOGY (2019)
Guadecitabine Plus Ipilimumab in Unresectable Melanoma: The NIBIT-M4 Clinical Trial
Anna Maria Di Giacomo et al.
CLINICAL CANCER RESEARCH (2019)
Isovitexin Suppresses Cancer Sternness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis
Xiao Liang et al.
CANCER MANAGEMENT AND RESEARCH (2019)
Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression
Christopher Groth et al.
BRITISH JOURNAL OF CANCER (2019)
Downregulation of miR-152 contributes to DNMT1-mediated silencing of SOCS3/SHP-1 in non-Hodgkin lymphoma
Qing-Ming Wang et al.
CANCER GENE THERAPY (2019)
EZH2-DNMT1-mediated epigenetic silencing of miR-142-3p promotes metastasis through targeting ZEB2 in nasopharyngeal carcinoma
Yingqin Li et al.
CELL DEATH AND DIFFERENTIATION (2019)
Zebularine and trichostatin A sensitized human breast adenocarcinoma cells towards tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis
Wei Yang Kong et al.
HELIYON (2019)
Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, a DNMT3B in Acute Myeloid Leukaemia
Kah Keng Wong et al.
BIOMARKER INSIGHTS (2019)
Ilamycin E, a natural product of marine actinomycete, inhibits triple-negative breast cancer partially through ER stress-CHOP-Bcl-2
Wenhui Zhou et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
Frank Lyko
NATURE REVIEWS GENETICS (2018)
Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer
Maria Vittoria Dieci et al.
SEMINARS IN CANCER BIOLOGY (2018)
Breast cancer genomics and immuno-oncological markers to guide immune therapies
D. Hammerl et al.
SEMINARS IN CANCER BIOLOGY (2018)
The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts
Layla A. Al-Kharashi et al.
ONCOTARGET (2018)
Linc00152 promotes tumorigenesis by regulating DNMTs in triple-negative breast cancer
Jiali Wu et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Mutant p53 in breast cancer: potential as a therapeutic target and biomarker
Michael J. Duffy et al.
BREAST CANCER RESEARCH AND TREATMENT (2018)
TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer
Charly Ryan Good et al.
CANCER RESEARCH (2018)
An androgen receptor negatively induced long non-coding RNA ARNILA binding to miR-204 promotes the invasion and metastasis of triple-negative breast cancer
Fang Yang et al.
CELL DEATH AND DIFFERENTIATION (2018)
Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer
Wei Li et al.
CELL METABOLISM (2018)
MiR-137 Suppresses Triple-Negative Breast Cancer Stemness and Tumorigenesis by Perturbing BCL11A-DNMT1 Interaction
Feiyu Chen et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With Regard to Invasion and Metastasis of Breast Cancer
Nami Yamashita et al.
CLINICAL BREAST CANCER (2018)
A Phase I Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic Analyses
Daniela Matei et al.
CLINICAL CANCER RESEARCH (2018)
An Effective Epigenetic-PARP Inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA Mutations
Nicholas Pulliam et al.
CLINICAL CANCER RESEARCH (2018)
Cisplatin inhibits the progression of bladder cancer by selectively depleting G-MDSCs: A novel chemoimmunomodulating strategy
Ke Wu et al.
CLINICAL IMMUNOLOGY (2018)
EMT in Metastasis: Finding the Right Balance
Hin Ching Lo et al.
DEVELOPMENTAL CELL (2018)
NUSAP1 gene silencing inhibits cell proliferation, migration and invasion through inhibiting DNMT1 gene expression in human colorectal cancer
Guoda Han et al.
EXPERIMENTAL CELL RESEARCH (2018)
Altered DNA methyltransferases promoter methylation and mRNA expression are associated with tamoxifen response in breast tumors
Rosa Jahangiri et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine
Jia Yu et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Anti-Tumorigenic and Anti-Metastatic Activity of the Sponge-Derived Marine Drugs Aeroplysinin-1 and Isofistularin-3 against Pheochromocytoma In Vitro
Nicole Bechmann et al.
MARINE DRUGS (2018)
A circular RNA circ-DNMT1 enhances breast cancer progression by activating autophagy
William W. Du et al.
ONCOGENE (2018)
DNMT1 is associated with cell cycle and DNA replication gene sets in diffuse large B-cell lymphoma
Suet Kee Loo et al.
PATHOLOGY RESEARCH AND PRACTICE (2018)
Epigenetics of breast cancer: Biology and clinical implication in the era of precision medicine
Barbara Pasculli et al.
SEMINARS IN CANCER BIOLOGY (2018)
DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer
Na Luo et al.
NATURE COMMUNICATIONS (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
The EZH2-H3K27me3-DNMT1 complex orchestrates epigenetic silencing of the wwc1 gene, a Hippo/YAP pathway upstream effector, in breast cancer epithelial cells
Xiong Liu et al.
CELLULAR SIGNALLING (2018)
ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer
Sushil Kumar et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Epigenetic reprogramming of epithelial mesenchymal transition in triple negative breast cancer cells with DNA methyltransferase and histone deacetylase inhibitors
Yanrong Su et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Inhibitors of DNA Methyltransferases From Natural Sources: A Computational Perspective
Fernanda I. Saldivar-Gonzalez et al.
FRONTIERS IN PHARMACOLOGY (2018)
Inhibitors targeting CDK4/6, PARP and PI3K in breast cancer: a review
Siti Muhamad Nur Husna et al.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)
Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity
Ying Bai et al.
JOURNAL OF NEUROSCIENCE (2018)
Dose, Schedule, Safety, and Efficacy of Guadecitabine in Relapsed or Refractory Acute Myeloid Leukemia
Gail J. Roboz et al.
CANCER (2018)
A Phase I Trial of a Guadecitabine (SGI-110) and Irinotecan in Metastatic Colorectal Cancer Patients Previously Exposed to Irinotecan
Valerie Lee et al.
CLINICAL CANCER RESEARCH (2018)
Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study
Roisin M. Connolly et al.
CLINICAL CANCER RESEARCH (2017)
DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression
Irina V. Pronina et al.
GENE (2017)
Zebularine Treatment Induces MAGE-A11 Expression and Improves CTL Cytotoxicity Using a Novel Identified HLA-A2-restricted MAGE-A11 Peptide
Jiandong Zhang et al.
JOURNAL OF IMMUNOTHERAPY (2017)
Identification of potent inhibitors of DNA methyltransferase 1 (DNMT1) through a pharmacophore-based virtual screening approach
Shagun Krishna et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2017)
Guadecitabine (SGI-110) in treatment-naive patients with acute myeloid leukaemia: phase 2 results from a multicentre, randomised, phase 1/2 trial
Hagop M. Kantarjian et al.
LANCET ONCOLOGY (2017)
DNMT1 is predictive of survival and associated with Ki-67 expression in R-CHOP-treated diffuse large B-cell lymphomas
Suet Kee Loo et al.
PATHOLOGY (2017)
Physcion 8-O-β-glucopyranoside suppresses the metastasis of breast cancer in vitro and in vivo by modulating DNMT1
Xia Chen et al.
PHARMACOLOGICAL REPORTS (2017)
Claudin-Low Breast Cancer; Clinical & Pathological Characteristics
Kay Dias et al.
PLOS ONE (2017)
miRNA-148a regulates the expression of the estrogen receptor through DNMT1-mediated DNA methylation in breast cancer cells
Yurui Xu et al.
ONCOLOGY LETTERS (2017)
DNA methylation at enhancers identifies distinct breast cancer lineages
Thomas Fleischer et al.
NATURE COMMUNICATIONS (2017)
Doxycycline inhibits breast cancer EMT and metastasis through PAR-1/NF-κB/miR-17/E-cadherin pathway
Weilong Zhong et al.
ONCOTARGET (2017)
HDAC inhibition potentiates immunotherapy in triple negative breast cancer
Manuela Terranova-Barberio et al.
ONCOTARGET (2017)
Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer
Elvira Donnarumma et al.
ONCOTARGET (2017)
Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells
Anna Lewinska et al.
THERANOSTICS (2017)
MiR-340 Inhibits Triple-Negative Breast Cancer Progression by Reversing EZH2 Mediated miRNAs Dysregulated Expressions
Zhendong Shi et al.
JOURNAL OF CANCER (2017)
Targeting long non-coding RNA DANCR inhibits triple negative breast cancer progression
Sha Sha et al.
BIOLOGY OPEN (2017)
Circular RNAs (circRNAs) in Health and Disease
Shahnaz Haque et al.
GENES (2017)
Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015 A Systematic Analysis for the Global Burden of Disease Study
Christina Fitzmaurice et al.
JAMA ONCOLOGY (2017)
Long non-coding RNA ANRIL promotes carcinogenesis via sponging miR-199a in triple-negative breast cancer
Shuang-Ta Xu et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple-negative breast cancer
Charli Dominguez et al.
JCI INSIGHT (2017)
Long non-coding RNA MALAT1 promotes proliferation and invasion via targeting miR-129-5p in triple-negative breast cancer
Yonggang Zuo et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
LncRNA-SNHG1 contributes to gastric cancer cell proliferation by regulating DNMT1
Yongbo Hu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Tamoxifen reverses epithelial mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells
Qian Wang et al.
BMC CANCER (2017)
DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies
Dany Pechalrieu et al.
BIOCHEMICAL PHARMACOLOGY (2017)
Epigenetics and approaches to targeted epigenetic therapy in acute myeloid leukemia
Bas J. Wouters et al.
BLOOD (2016)
Global Cancer Incidence and Mortality Rates and Trends-An Update
Lindsey A. Torre et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2016)
RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors
Sherene Loi et al.
CLINICAL CANCER RESEARCH (2016)
Cell Cycle Modulation of MCF-7 and MDA-MB-231 by a Sub-Fraction of Strobilanthes crispus and its Combination with Tamoxifen
Nik Soriani Yaacob et al.
Asian Pacific Journal of Cancer Prevention (2016)
The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair
Diana H. Liang et al.
CANCER LETTERS (2016)
Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Dongjun Peng et al.
CANCER RESEARCH (2016)
Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer
Reema Wahdan-Alaswad et al.
CELL CYCLE (2016)
DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop
Dipta Sengupta et al.
EXPERIMENTAL CELL RESEARCH (2016)
被撤回的出版物: Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis (Retracted article. See vol. 42, 2023)
Li Huang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Differential expression of the epigenetic methylation-related protein DNMT1 by breast cancer molecular subtype and stromal histology
Eunah Shin et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2016)
Higher levels of TIMP-1 expression are associated with a poor prognosis in triple-negative breast cancer
Guangcun Cheng et al.
MOLECULAR CANCER (2016)
Potent and selective bivalent inhibitors of BET bromodomains
Michael J. Waring et al.
NATURE CHEMICAL BIOLOGY (2016)
Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
Giampaolo Bianchini et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2016)
TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program
Yanzhou Zhang et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2016)
The correlation between DNMT1 and ER expression and the methylation status of ER, and its clinical significance in breast cancer
Weijie Zhang et al.
ONCOLOGY LETTERS (2016)
DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer
Andrew E. Teschendorff et al.
NATURE COMMUNICATIONS (2016)
Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells
Cristina Florean et al.
ONCOTARGET (2016)
Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer
Ken Takai et al.
ONCOTARGET (2016)
Notch3 inhibits epithelial-mesenchymal transition by activating Kibra-mediated Hippo/YAP signaling in breast cancer epithelial cells
X. Zhang et al.
ONCOGENESIS (2016)
Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis
Yun-Cheng Lv et al.
PLOS ONE (2016)
PD-L1 protein expression in breast cancer is rare, enriched in basal-like tumours and associated with infiltrating lymphocytes
H. R. Ali et al.
ANNALS OF ONCOLOGY (2015)
DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
David Roulois et al.
CELL (2015)
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
Katherine B. Chiappinelli et al.
CELL (2015)
Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts
Pragya Srivastava et al.
EPIGENETICS (2015)
Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study
Jean-Pierre J. Issa et al.
LANCET ONCOLOGY (2015)
Total Synthesis of (+)-Antroquinonol and (+)-Antroquinonol D
Rohidas S. Sulake et al.
ORGANIC LETTERS (2015)
Targeting DNA Methylation with Green Tea Catechins
Eugenia C. Yiannakopoulou
PHARMACOLOGY (2015)
The possible role of EZH2 and DNMT1 polymorphisms in sporadic triple-negative breast carcinoma in southern Chinese females
Ran Tao et al.
TUMOR BIOLOGY (2015)
DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis
Rajneesh Pathania et al.
NATURE COMMUNICATIONS (2015)
Target prediction utilising negative bioactivity data covering large chemical space
Lewis H. Mervin et al.
JOURNAL OF CHEMINFORMATICS (2015)
Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer
Michael T. Barrett et al.
ONCOTARGET (2015)
A gene expression signature identifying transient DNMT1 depletion as a causal factor of cancer-germline gene activation in melanoma
Julie Cannuyer et al.
CLINICAL EPIGENETICS (2015)
DNA Methyltransferase 1/3a Overexpression in Sporadic Breast Cancer is Associated with Reduced Expression of Estrogen Receptor-Alpha/Breast Cancer Susceptibility Gene 1 and Poor Prognosis
Zhaojin Yu et al.
MOLECULAR CARCINOGENESIS (2015)
Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells
Yan Zhuang et al.
MOLECULAR CARCINOGENESIS (2015)
A DNA methylation-based definition of biologically distinct breast cancer subtypes
Olafur A. Stefansson et al.
MOLECULAR ONCOLOGY (2015)
δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells
Akihiko Fukagawa et al.
CANCER MEDICINE (2015)
The fate of chemoresistance in triple negative breast cancer (TNBC)
Elma A. O'Reilly et al.
BBA CLINICAL (2015)
miR-185 Inhibits Hepatocellular Carcinoma Growth by Targeting the DNMT1/PTEN/Akt Pathway
Ximena V. Qadir et al.
AMERICAN JOURNAL OF PATHOLOGY (2014)
Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: a retrospective multicenter study
M. V. Dieci et al.
ANNALS OF ONCOLOGY (2014)
Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions
Hao Wu et al.
CELL (2014)
Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer
Suganthi Chittaranjan et al.
CLINICAL CANCER RESEARCH (2014)
The de novo DNA methyltransferase DNMT3A in development and cancer
Bi-Feng Chen et al.
EPIGENETICS (2014)
Genistein inhibits DNA methylation and increases expression of tumor suppressor genes in human breast cancer cells
Qi Xie et al.
GENES CHROMOSOMES & CANCER (2014)
Antroquinonol D, Isolated from Antrodia camphorata, with DNA Demethylation and Anticancer Potential
Sheng-Chao Wang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)
Total Synthesis of (±)-Antroquinonol D
Rohidas S. Sulake et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
Decreased miR-30b-5p expression by DNMT1 methylation regulation involved in gastric cancer metastasis
Fengchang Qiao et al.
MOLECULAR BIOLOGY REPORTS (2014)
Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents
H. Yang et al.
LEUKEMIA (2014)
Immunomodulatory action of SGI-110, a hypomethylating agent, in acute myeloid leukemia cells and xenografts
Pragya Srivastava et al.
LEUKEMIA RESEARCH (2014)
Prognostic significance of let-7b expression in breast cancer and correlation to its target gene of BSG expression
Lin Ma et al.
MEDICAL ONCOLOGY (2014)
Measures of Outcome in Metastatic Breast Cancer: Insights From a Real-World Scenario
Marta Bonotto et al.
ONCOLOGIST (2014)
Identification of Kazinol Q, a Natural Product from Formosan Plants, as an Inhibitor of DNA Methyltransferase
Jing-Ru Weng et al.
PHYTOTHERAPY RESEARCH (2014)
Chloroquine Eliminates Cancer Stem Cells Through Deregulation of Jak2 and DNMT1
Dong Soon Choi et al.
STEM CELLS (2014)
Basal-Like and Triple-Negative Breast Cancers Searching for Positives Among Many Negatives
Prasanna Alluri et al.
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA (2014)
New concepts in DNA methylation
Albert Jeltsch et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease
Riadh Ben Gacem et al.
TUMOR BIOLOGY (2014)
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers
Huili Li et al.
ONCOTARGET (2014)
Expression profiling of DNA methylation-mediated epigenetic gene-silencing factors in breast cancer
Swayamsiddha Kar et al.
CLINICAL EPIGENETICS (2014)
DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML
Kirstin Lund et al.
GENOME BIOLOGY (2014)
Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells
P. Liu et al.
BRITISH JOURNAL OF CANCER (2013)
Immunomodulatory activity of SGI-110, a 5-aza-2′-deoxycytidine-containing demethylating dinucleotide
Sandra Coral et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Interplay between the Cancer Genome and Epigenome
Hui Shen et al.
CELL (2013)
Myeloid-Derived Suppressor Cells Enhance Stemness of Cancer Cells by Inducing MicroRNA101 and Suppressing the Corepressor CtBP2
Tracy X. Cui et al.
IMMUNITY (2013)
Expression of DNA Methyltransferases in Breast Cancer Patients and to Analyze the Effect of Natural Compounds on DNA Methyltransferases and Associated Proteins
Sameer Mirza et al.
JOURNAL OF BREAST CANCER (2013)
In Silico Target Predictions: Defining a Benchmarking Data Set and Comparison of Performance of the Multiclass Naive Bayes and Parzen-Rosenblatt Window
Alexios Koutsoukas et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2013)
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor
Louise J. Barber et al.
JOURNAL OF PATHOLOGY (2013)
Mutant p53 binds to estrogen receptor negative promoter via DNMT1 and HDAC1 in MDA-MB-468 breast cancer cells
Rita Arabsolghar et al.
MOLECULAR BIOLOGY REPORTS (2013)
HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regulate the NY-ESO1 gene expression
Pierre-Francois Cartron et al.
MOLECULAR ONCOLOGY (2013)
Natural RNA circles function as efficient microRNA sponges
Thomas B. Hansen et al.
NATURE (2013)
DNA methylation: roles in mammalian development
Zachary D. Smith et al.
NATURE REVIEWS GENETICS (2013)
DNMT1 genetic polymorphisms affect breast cancer risk in the central European Caucasian population
Kathrin Kullmann et al.
CLINICAL EPIGENETICS (2013)
Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers
Riadh Ben Gacem et al.
HUMAN PATHOLOGY (2012)
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
Chenfang Dong et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Noncoding RNAs Involved in Mammary Gland Development and Tumorigenesis: There's a Long Way to Go
Amy N. Shore et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2012)
DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer
Min Chen et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Combination of Pan-Histone Deacetylase Inhibitor and Autophagy Inhibitor Exerts Superior Efficacy against Triple-Negative Human Breast Cancer Cells
Rekha Rao et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Comprehensive molecular portraits of human breast tumours
Daniel C. Koboldt et al.
NATURE (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
5-Aza-2′-deoxycytidine-induced genome rearrangements are mediated by DNMT1
A. Y. Maslov et al.
ONCOGENE (2012)
Arsenic Induces Functional Re-Expression of Estrogen Receptor α by Demethylation of DNA in Estrogen Receptor-Negative Human Breast Cancer
Juan Du et al.
PLOS ONE (2012)
Correction: NY-ESO-1 Cancer Testis Antigen Demonstrates High Immunogenicity in Triple Negative Breast Cancer
Foluso O. Ademuyiwa et al.
PLoS One (2012)
A snapshot of chemoresistance to PARP inhibitors
Alberto Chiarugi
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Coordinated regulation of myeloid cells by tumours
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Strategies for subtypes-dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011
A. Goldhirsch et al.
ANNALS OF ONCOLOGY (2011)
MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1
Hui Wang et al.
CARCINOGENESIS (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Paired Immunoglobin-like Receptor-B Regulates the Suppressive Function and Fate of Myeloid-Derived Suppressor Cells
Ge Ma et al.
IMMUNITY (2011)
Kazinol Q from Broussonetia kazinoki Enhances Cell Death Induced by Cu(II) through Increased Reactive Oxygen Species
Bai-Luh Wei et al.
MOLECULES (2011)
Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis
Fang Fang et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Basal-like breast cancer displays distinct patterns of promoter methylation
Ji Shin Lee et al.
CANCER BIOLOGY & THERAPY (2010)
Association of DNMT1 Gene Polymorphisms in Exons With Sporadic Infiltrating Ductal Breast Carcinoma Among Chinese Han Women in the Heilongjiang Province
Gao Xiang et al.
CLINICAL BREAST CANCER (2010)
Impact on DNA Methylation in Cancer Prevention and Therapy by Bioactive Dietary Components
Y. Li et al.
CURRENT MEDICINAL CHEMISTRY (2010)
Epigenetic modifications as therapeutic targets
Theresa K. Kelly et al.
NATURE BIOTECHNOLOGY (2010)
Sulforaphane Causes Epigenetic Repression of hTERT Expression in Human Breast Cancer Cell Lines
Syed M. Meeran et al.
PLOS ONE (2010)
Locoregional Recurrence of Triple-negative Breast Cancer After Breast-conserving Surgery and Radiation
Gary M. Freedman et al.
CANCER (2009)
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
Mamta Tahiliani et al.
SCIENCE (2009)
Phase I Study of Epigenetic Modulation with 5-Azacytidine and Valproic Acid in Patients with Advanced Cancers
Fadi Braiteh et al.
CLINICAL CANCER RESEARCH (2008)
Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine
Carlo Stresemann et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Delivery of 5-aza-2′-deoxycytidine to cells using oligodeoxynucleotides
Christine B. Yoo et al.
CANCER RESEARCH (2007)
The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
Lisa A. Carey et al.
CLINICAL CANCER RESEARCH (2007)
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
Taiping Chen et al.
NATURE GENETICS (2007)
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
Fabio Spada et al.
JOURNAL OF CELL BIOLOGY (2007)
Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b
S. R. James et al.
ONCOGENE (2006)
Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells
A Loriot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Release of methyl CpG binding proteins and histone deacetylase 1 from the estrogen receptor α (ER) promoter upon reactivation in ER-negative human breast cancer cells
D Sharma et al.
MOLECULAR ENDOCRINOLOGY (2005)
Preferential response of cancer cells to zebularine
JC Cheng et al.
CANCER CELL (2004)
Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor α (ER) in ER-negative human breast cancer cell lines
L Yan et al.
CANCER BIOLOGY & THERAPY (2003)
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
MF Robert et al.
NATURE GENETICS (2003)