Related references
Note: Only part of the references are listed.Single-cell RNA-seq analysis reveals the progression of human osteoarthritis
Quanbo Ji et al.
ANNALS OF THE RHEUMATIC DISEASES (2019)
Blocking of YY1 reduce neutrophil infiltration by inhibiting IL-8 production via the PI3K-Akt-mTOR signaling pathway in rheumatoid arthritis
J. Lin et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2019)
Role of Epigenomics in Bone and Cartilage Disease
Joyce B. J. van Meurs et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2019)
Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity
Kosuke Nishio et al.
CHEMBIOCHEM (2018)
Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter
Ruili Yang et al.
NATURE COMMUNICATIONS (2018)
Early Changes of Articular Cartilage and Subchondral Bone in The DMM Mouse Model of Osteoarthritis
Hang Fang et al.
SCIENTIFIC REPORTS (2018)
Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritis
Ye Liu et al.
SCIENTIFIC REPORTS (2018)
DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells
Tianpeng Gu et al.
GENOME BIOLOGY (2018)
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
Damian Szklarczyk et al.
NUCLEIC ACIDS RESEARCH (2017)
A critical role of transcription factor YY1 in rheumatoid arthritis by regulation of interleukin-6
Jinpiao Lin et al.
JOURNAL OF AUTOIMMUNITY (2017)
A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer
Charly R. Good et al.
NUCLEIC ACIDS RESEARCH (2017)
An epigenetic switch repressing Tet1 in gonadotropes activates the reproductive axis
Yahav Yosefzon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes
Marian Mellen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
DOT1L safeguards cartilage homeostasis and protects against osteoarthritis
Silvia Monteagudo et al.
NATURE COMMUNICATIONS (2017)
Age-dependent Changes in the Articular Cartilage and Subchondral Bone of C57BL/6 Mice after Surgical Destabilization of Medial Meniscus
Henry Huang et al.
SCIENTIFIC REPORTS (2017)
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism
Jie Shen et al.
JCI INSIGHT (2017)
Stable 5-Hydroxymethylcytosine (5hmC) Acquisition Marks Gene Activation During Chondrogenic Differentiation
Sarah E. B. Taylor et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2016)
Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases
Esta Tamanaha et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
The extracellular matrix: Tools and insights for the omics era
Alexandra Naba et al.
MATRIX BIOLOGY (2016)
Isoform Switch of TET1 Regulates DNA Demethylation and Mouse Development
Wenhao Zhang et al.
MOLECULAR CELL (2016)
Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
William H. Robinson et al.
NATURE REVIEWS RHEUMATOLOGY (2016)
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
Maxim V. Kuleshov et al.
NUCLEIC ACIDS RESEARCH (2016)
Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage
Matlock A. Jeffries et al.
ARTHRITIS & RHEUMATOLOGY (2016)
Osteoarthritis
Johanne Martel-Pelletier et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis
Nan Mu et al.
SCIENTIFIC REPORTS (2016)
State of the evidence
Kelli D. Allen et al.
CURRENT OPINION IN RHEUMATOLOGY (2015)
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6
Qian Zhang et al.
NATURE (2015)
Transcriptional Associations of Osteoarthritis-Mediated Loss of Epigenetic Control in Articular Cartilage
Wouter den Hollander et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Genome-Wide Mapping of DNA Hydroxymethylation in Osteoarthritic Chondrocytes
Sarah E. B. Taylor et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients
Juan Fernandez-Tajes et al.
ANNALS OF THE RHEUMATIC DISEASES (2014)
Modulation of Ten-Eleven Translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) Expression, α-Ketoglutarate (α-KG), and DNA Hydroxymethylation Levels by Interleukin-1β in Primary Human Chondrocytes
Abdul Haseeb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
5-Hydroxymethylcytosine is a predominantly stable DNA modification
Martin Bachman et al.
NATURE CHEMISTRY (2014)
A Global Increase in 5-Hydroxymethylcytosine Levels Marks Osteoarthritic Chondrocytes
Sarah E. B. Taylor et al.
ARTHRITIS & RHEUMATOLOGY (2014)
Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis
Michael D. Rushton et al.
ARTHRITIS & RHEUMATOLOGY (2014)
RRHP: a tag-based approach for 5-hydroxymethylcytosine mapping at single-site resolution
Adam Petterson et al.
GENOME BIOLOGY (2014)
Loss of methylation in CpG sites in the NF-B enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes
Maria C. de Andres et al.
ARTHRITIS AND RHEUMATISM (2013)
Annexin A6 Interacts With p65 and Stimulates NF-κB Activity and Catabolic Events in Articular Chondrocytes
Kirk A. Campbell et al.
ARTHRITIS AND RHEUMATISM (2013)
Class I Histone Deacetylase Inhibition Modulates Metalloproteinase Expression and Blocks Cytokine-Induced Cartilage Degradation
Kirsty L. Culley et al.
ARTHRITIS AND RHEUMATISM (2013)
A rare variant in the osteoarthritis-associated locus GDF5 is functional and reveals a site that can be manipulated to modulate GDF5 expression
Andrew W. Dodd et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2013)
ATDC5: An excellent in vitro model cell line for skeletal development
Yongchang Yao et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2013)
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
William A. Pastor et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Disease Progression and Phasic Changes in Gene Expression in a Mouse Model of Osteoarthritis
Richard F. Loeser et al.
PLOS ONE (2013)
Dynamics of 5-Hydroxymethylcytosine and Chromatin Marks in Mammalian Neurogenesis
Maria A. Hahn et al.
CELL REPORTS (2013)
Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells
Francesco Neri et al.
GENOME BIOLOGY (2013)
Osteoarthritis: A disease of the joint as an organ
Richard F. Loeser et al.
ARTHRITIS AND RHEUMATISM (2012)
cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis
Catherine Bui et al.
FASEB JOURNAL (2012)
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity
Johannes M. Freudenberg et al.
NUCLEIC ACIDS RESEARCH (2012)
Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis
Martha C. Castano Betancourt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
Wei Xu et al.
CANCER CELL (2011)
Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development
Meelad M. Dawlaty et al.
CELL STEM CELL (2011)
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Rasheduzzaman Chowdhury et al.
EMBO REPORTS (2011)
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
Hao Wu et al.
GENES & DEVELOPMENT (2011)
Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation
Louise N. Reynard et al.
HUMAN MOLECULAR GENETICS (2011)
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse
S. S. Glasson et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse
S. S. Glasson et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Osteoarthritis severity is sex dependent in a surgical mouse model
H. -L. Ma et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions
HI Roach et al.
ARTHRITIS AND RHEUMATISM (2005)
Production of the chemokine eotaxin-1 in osteoarthritis and its role in cartilage degradation
YH Hsu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Evidence for a key role of leptin in osteoarthritis
H Dumond et al.
ARTHRITIS AND RHEUMATISM (2003)
IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways
JA Mengshol et al.
NUCLEIC ACIDS RESEARCH (2001)