4.8 Review

Social determinants of health and survival in humans and other animals

Journal

SCIENCE
Volume 368, Issue 6493, Pages 843-+

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aax9553

Keywords

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Funding

  1. Duke Center for Population Health and Aging
  2. NIH [P30AG034424, P2C HD050924, R01AG057235, R01HD088558, R01GM102562, R00AG051764, R01AG060931, T32AG000139, R01HL087103, R01AG057800, R24AG065172, R01AG053308, P01AG031719, P01HD031921, R01HD087061]
  3. Carolina Population Center
  4. Triangle Center for Evolutionary Medicine
  5. Duke Social Sciences Research Institute
  6. Human Frontier Science Program Research Grant
  7. Minnesota Partnership for Biotechnology and Medical Genomics [18.04]
  8. Jacobs Foundation Early Career Fellowship
  9. Bridging Biodiversity and Conservation Science program at the University of Arizona
  10. National Inst of Health [F32HD084117, R01DK102496, R01MD013349, R01MD011728, T32HD091058, 1K99AG062749-01A1, T32HD007168, T32AG000029]

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The social environment, both in early life and adulthood, is one of the strongest predictors of morbidity and mortality risk in humans. Evidence from long-term studies of other social mammals indicates that this relationship is similar across many species. In addition, experimental studies show that social interactions can causally alter animal physiology, disease risk, and life span itself. These findings highlight the importance of the social environment to health and mortality as well as Darwinian fitness-outcomes of interest to social scientists and biologists alike. They thus emphasize the utility of cross-species analysis for understanding the predictors of, and mechanisms underlying, social gradients in health.

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