Journal
CHEMISTRY LETTERS
Volume 45, Issue 3, Pages 242-249Publisher
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.151176
Keywords
Drug delivery; Nanocarrier; Stimuli-responsive system
Categories
Funding
- National Natural Science Foundation of China [21271101, 91213305]
- National Basic Research Program of China [2015CB856300]
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Drug release in a spatially and temporally controlled manner is highly desired in the field of drug delivery. Endogenous stimuli responsive nanocarriers provide significant advantages in maximizing the therapeutic efficacy and minimizing the side effects of loaded drugs. Biomarker-triggered release and site-specific delivery are the most commonly adopted strategies. In this review, the most recent advances in the field of endogenous stimuli-responsive drug delivery nanocarriers and their potential application in the treatment of various diseases are highlighted and discussed.
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