Journal
RHEUMATOLOGY
Volume 59, Issue -, Pages 95-100Publisher
OXFORD UNIV PRESS
DOI: 10.1093/rheumatology/kez599
Keywords
childhood vasculitis; Kawasaki; IgA vasculitis; PAN; SAVI; deficiency of ADA2
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Funding
- University of Cambridge
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Vasculitis is a challenging disease for paediatricians. Certain vasculitides are quite common in children whereas others are much rarer compared with adults. The most common vasculitides in childhood are IgA-associated vasculitis (Henoch-Schonlein purpura) and Kawasaki disease, which are usually self-limiting vasculitides although children do develop complications as a result. We now have much better knowledge of how to manage these patients and prevent the deleterious complications. This review provides an up-to-date discussion on childhood vasculitides, including diagnosis, treatment and follow-up strategies, together with a comparison with vasculitides in adults. It also discusses the newly defined monogenic vasculitides that often present during early childhood.
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