Bioactive Constituents from the Rhizomes of Sansevieria cylindrica

Analysis of the MeOH extract of rhizomes of Sansevieria cylindrica using repeated silica gel and reversed-phase chromatographic separations led to the isolation of ten known phenolic compounds (1-10) belonging to five different classes. Their structures, including the absolute configuration, were identified by NMR and CD spectra analysis. The antiradical activity of isolated compounds was screened using the DPPH scavenging method. The cytotoxic effects were assayed against a Hela cell line. Compounds 2-10 have been isolated from a Sansevieria species for the first time and compounds 5, 7-10 have been isolated from species of the Asparagaceae family for the first time. The structure of a homoisoflavanone isolated from S. roxburghiana has been revised.