Journal
PLANT AND CELL PHYSIOLOGY
Volume 61, Issue 11, Pages 1869-1879Publisher
OXFORD UNIV PRESS
DOI: 10.1093/pcp/pcaa051
Keywords
Anabolism; Catabolism; GA-oxidases; Gibberellin biosynthesis; Multifunctional enzymes; 2-Oxoglutarate-dependent dioxygenases
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Funding
- VolkswagenStiftung [95 475]
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Gibberellin (GA) hormones regulate the development of plants and their responses to environmental signals. The final part of GA biosynthesis is catalyzed by multifunctional 2-oxoglutarate-dependent dioxygenases, which are encoded by multigene families. According to their enzymatic properties and physiological functions, GA-oxidases are classified as anabolic or catabolic enzymes. Together they allow complex regulation of the GA biosynthetic pathway, which adapts the specific hormonal needs of a plant during development and interaction with its environment. In this review, we combine recent advances in enzymatic characterization of the multifunctional GA-oxidases, in particular, from cucumber and Arabidopsis that have been most comprehensively investigated.
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