Journal
PHARMACEUTICAL RESEARCH
Volume 37, Issue 6, Pages -Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s11095-020-02842-8
Keywords
ammonium chloride; antiseptic; cetylpyridinium chloride; SARS-CoV-2
Funding
- NIH: NIGMS [R44GM122196-02A1]
- NIH: NCATS [R21TR001718]
- NIH: NCCAM [R43AT010585-01S1]
- NIH [1OT2TR002514-01]
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The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with well-known broad-spectrum antiviral activities and represent a repurposing opportunity as therapeutics against SARS-CoV-2.
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