Journal
ORGANIC LETTERS
Volume 22, Issue 9, Pages 3351-3355Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c00779
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21472019]
Ask authors/readers for more resources
A simple, direct, and highly enantioselective synthesis of spiro-oxindole piperidin-2-one derivatives was achieved through an aza-Michael/Michael cyclization cascade sequence using a squaramide catalyst. The desired products were obtained in excellent yields (up to 99%) and good to high stereoselectivities (up to >20:1 dr and up to 99% ee) under mild conditions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available