Journal
CHEMICAL REVIEWS
Volume 116, Issue 7, Pages 4441-4557Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.chemrev.5b00712
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Funding
- National Institutes of Health (NIH) (National Institute of Environmental Health Sciences (NIEHS)) [R03 ES025345]
- National Institutes of Health (NIH) (National Institute of General Medical Sciences (NIGMS)) [R01 077379]
- National Science Foundation (NSF) [CHE 1463819]
- NSF Graduate Fellowship Program
- Direct For Mathematical & Physical Scien [1463819] Funding Source: National Science Foundation
- Division Of Chemistry [1463819] Funding Source: National Science Foundation
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The main objective of this review is to provide a comprehensive survey of methods used for stereoselective construction of carbon-nitrogen bonds during the total synthesis of nitrogen-containing natural products that have appeared in the literature since 2000. The material is organized by specific reaction in order of decreasing number of applications in natural product synthesis. About 800 total syntheses of natural products with stereogenic carbon-nitrogen bonds described since 2000 have been reviewed.
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