Serum Inflammation Biomarkers in Patients with Keratoconus

Purpose: To evaluate inflammation-sensitive parameters, namely the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), eosinophil count, erythrocyte distribution width (RDW), and CRP/albumin ratio in patients with keratoconus (KC). Methods: Thirty-five patients with KC and 30 healthy people (control group) were included in the study. Complete blood count measurements were performed in all subjects, and NLR, PLR and the CRP/albumin ratio were calculated. Results: NLR was determined as 2.01 +/- 0.53 in patients with KC and 1.97 +/- 0.41 in the control group. PLR was 146.20 +/- 23.32 in the KC group and 121.45 +/- 31.75 in the healthy group. The CRP/albumin ratio was determined as 0.33 +/- 0.09 in the KC group and 0.29 +/- 0.11 in the healthy group. Conclusion: Although no significant difference was found between the groups in terms of NLR, CRP/albumin ratio and RDW levels, PLR was significantly higher in the KC group.

Automated summary

The study aimed to evaluate inflammation-sensitive parameters in patients with KC, and the results showed that PLR was significantly higher in the KC group.