4.6 Article

Bio-/Chemosensors and Imaging with Aggregation-Induced Emission Luminogens

Journal

CHEMICAL RECORD
Volume 16, Issue 4, Pages 2142-2160

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.201600045

Keywords

aggregation; biosensors; chemosensors; fluorescent probes; imaging agents

Funding

  1. National Natural Science Foundation of China [21422207]
  2. Ministry of Science and Technology of China [2013CB834700, 2013CB733700]
  3. Chinese Academy of Sciences

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Aggregation-induced emission (AIE) luminogens show abnormal fluorescent behavior; they are non-emissive in solution, but they become strongly emissive after aggregation. Sensing and imaging are the major applications of AIE luminogens. By properly manipulating the aggregation and deaggregation of AIE molecules, various bio-/chemosensors have been developed. Moreover, AIE molecules with targeting groups have been devised for imaging of organelles and cancer cells. In this account, we report our recent work on the application of AIE lum(i)nogens for the construction of bio-/chemosensors and imaging.

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