Journal
NATURE REVIEWS DRUG DISCOVERY
Volume 19, Issue 4, Pages 221-223Publisher
NATURE RESEARCH
DOI: 10.1038/d41573-020-00050-y
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Drug-tolerant persisters, de novo mutations and pre-existing resistance are just some of the ways cancers evade the effects of anti-cancer drugs. Can new targets and new dosing strategies tackle evolutionary forces directly to delay the inevitable? Drug-tolerant persisters, de novo mutations and pre-existing resistance are just some of the ways cancers evade the effects of anti-cancer drugs. Can new targets and new dosing strategies tackle evolutionary forces directly to delay the inevitable?
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