Related references
Note: Only part of the references are listed.A statistical framework for cross-tissue transcriptome-wide association analysis
Yiming Hu et al.
NATURE GENETICS (2019)
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Laura M. Huckins et al.
NATURE GENETICS (2019)
Opportunities and challenges for transcriptome-wide association studies
Michael Wainberg et al.
NATURE GENETICS (2019)
Probabilistic fine-mapping of transcriptome-wide association studies
Nicholas Mancuso et al.
NATURE GENETICS (2019)
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection
Armin P. Schoech et al.
NATURE COMMUNICATIONS (2019)
Genes with High Network Connectivity Are Enriched for Disease Heritability
Samuel S. Kim et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants
Alexander Gusev et al.
NATURE GENETICS (2019)
Abundant associations with gene expression complicate GWAS follow-up
Boxiang Liu et al.
NATURE GENETICS (2019)
Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits
Eric R. Gamazon et al.
NATURE GENETICS (2019)
HUMAN GENOMICS Chromatin three-dimensional interactions mediate genetic effects on gene expression
O. Delaneau et al.
SCIENCE (2019)
Dynamic genetic regulation of gene expression during cellular differentiation
B. J. Strober et al.
SCIENCE (2019)
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
Eleonora Porcu et al.
NATURE COMMUNICATIONS (2019)
Extreme Polygenicity of Complex Traits Is Explained by Negative Selection
Luke J. O'Connor et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
Ultrarare variants drive substantial cis heritability of human gene expression
Ryan D. Hernandez et al.
NATURE GENETICS (2019)
Evidence for Weak Selective Constraint on Human Gene Expression
Emily C. Glassberg et al.
GENETICS (2019)
The Reactome Pathway Knowledgebase
Antonio Fabregat et al.
NUCLEIC ACIDS RESEARCH (2018)
DrugBank 5.0: a major update to the DrugBank database for 2018
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2018)
Transcriptome-wide association studies accounting for colocalization using Egger regression
Richard Barfield et al.
GENETIC EPIDEMIOLOGY (2018)
Evaluating the potential role of pleiotropy in Mendelian randomization studies
Gibran Hemani et al.
HUMAN MOLECULAR GENETICS (2018)
Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs
Monique G. P. van der Wijst et al.
NATURE GENETICS (2018)
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Naomi R. Wray et al.
NATURE GENETICS (2018)
Signatures of negative selection in the genetic architecture of human complex traits
Jian Zeng et al.
NATURE GENETICS (2018)
Mixed-model association for biobank-scale datasets
Po-Ru Loh et al.
NATURE GENETICS (2018)
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
Lang Wu et al.
NATURE GENETICS (2018)
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation
Eric R. Gamazon et al.
NATURE GENETICS (2018)
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits
Farhad Hormozdiari et al.
NATURE GENETICS (2018)
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Antonio F. Pardinas et al.
NATURE GENETICS (2018)
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
Hilary K. Finucane et al.
NATURE GENETICS (2018)
Efficient pathway enrichment and network analysis of GWAS summary data using GSA-SNP2
Sora Yoon et al.
NUCLEIC ACIDS RESEARCH (2018)
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
Alvaro N. Barbeira et al.
NATURE COMMUNICATIONS (2018)
The MR-Base platform supports systematic causal inference across the human phenome
Gibran Hemani et al.
ELIFE (2018)
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
Nicholas Mancuso et al.
NATURE COMMUNICATIONS (2018)
The UK Biobank resource with deep phenotyping and genomic data
Clare Bycroft et al.
NATURE (2018)
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
Michael J. Gandal et al.
SCIENCE (2018)
Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes
Xiang Zhu et al.
NATURE COMMUNICATIONS (2018)
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
Jacqueline MacArthur et al.
NUCLEIC ACIDS RESEARCH (2017)
KEGG: new perspectives on genomes, pathways, diseases and drugs
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2017)
Genetic effects on gene expression across human tissues
Francois Aguet et al.
NATURE (2017)
Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection
Steven Gazal et al.
NATURE GENETICS (2017)
Estimating the selective effects of heterozygous protein-truncating variants from human exome data
Christopher A. Cassa et al.
NATURE GENETICS (2017)
Estimating the causal tissues for complex traits and diseases
Halit Ongen et al.
NATURE GENETICS (2017)
Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types
Sung Chun et al.
NATURE GENETICS (2017)
Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
Traver Hart et al.
G3-GENES GENOMES GENETICS (2017)
10 Years of GWAS Discovery: Biology, Function, and Translation
Peter M. Visscher et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues
Xuanyao Liu et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
Colocalization of GWAS and eQTL Signals Detects Target Genes
Farhad Hormozdiari et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
Hendrik G. Stunnenberg et al.
CELL (2016)
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al.
NATURE (2016)
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
Zhihong Zhu et al.
NATURE GENETICS (2016)
Integrative approaches for large-scale transcriptome-wide association studies
Alexander Gusev et al.
NATURE GENETICS (2016)
The statistical properties of gene-set analysis
Christiaan A. de Leeuw et al.
NATURE REVIEWS GENETICS (2016)
RNA splicing is a primary link between genetic variation and disease
Yang I. Li et al.
SCIENCE (2016)
A global reference for human genetic variation
David M. Altshuler et al.
NATURE (2015)
Partitioning heritability by functional annotation using genome-wide association summary statistics
Hilary K. Finucane et al.
NATURE GENETICS (2015)
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Brendan K. Bulik-Sullivan et al.
NATURE GENETICS (2015)
Efficient Bayesian mixed-model analysis increases association power in large cohorts
Po-Ru Loh et al.
NATURE GENETICS (2015)
A gene-based association method for mapping traits using reference transcriptome data
Eric R. Gamazon et al.
NATURE GENETICS (2015)
Identification and characterization of essential genes in the human genome
Tim Wang et al.
SCIENCE (2015)
Biological interpretation of genome-wide association studies using predicted gene functions
Tune H. Pers et al.
NATURE COMMUNICATIONS (2015)
MAGMA: Generalized Gene-Set Analysis of GWAS Data
Christiaan A. de Leeuw et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
Genetic and epigenetic fine mapping of causal autoimmune disease variants
Kyle Kai-How Farh et al.
NATURE (2015)
Cross-Tissue and Tissue-Specific eQTLs: Partitioning the Heritability of a Complex Trait
Jason M. Torres et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2014)
A framework for the interpretation of de novo mutation in human disease
Kaitlin E. Samocha et al.
NATURE GENETICS (2014)
ClinVar: public archive of relationships among sequence variation and human phenotype
Melissa J. Landrum et al.
NUCLEIC ACIDS RESEARCH (2014)
Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
Benjamin P. Fairfax et al.
SCIENCE (2014)
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
Claudia Giambartolomei et al.
PLOS GENETICS (2014)
dbNSFP v2.0: A Database of Human Non-synonymous SNVs and Their Functional Predictions and Annotations
Xiaoming Liu et al.
HUMAN MUTATION (2013)
Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture
Lea K. Davis et al.
PLOS GENETICS (2013)
From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes
Benjamin Georgi et al.
PLOS GENETICS (2013)
INRICH: interval-based enrichment analysis for genome-wide association studies
Phil H. Lee et al.
BIOINFORMATICS (2012)
Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses
Oliver Stegle et al.
NATURE PROTOCOLS (2012)
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Matthew T. Maurano et al.
SCIENCE (2012)
GCTA: A Tool for Genome-wide Complex Trait Analysis
Jian Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
Molecular signatures database (MSigDB) 3.0
Arthur Liberzon et al.
BIOINFORMATICS (2011)
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
Jennifer C. Darnell et al.
CELL (2011)
The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics
Judith A. Blake et al.
NUCLEIC ACIDS RESEARCH (2011)
Single-Tissue and Cross-Tissue Heritability of Gene Expression Via Identity-by-Descent in Related or Unrelated Individuals
Alkes L. Price et al.
PLOS GENETICS (2011)
Integrating common and rare genetic variation in diverse human populations
David M. Altshuler et al.
NATURE (2010)
Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits
Ayellet V. Segre et al.
PLOS GENETICS (2010)
PLINK: A tool set for whole-genome association and population-based linkage analyses
Shaun Purcell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Regulation of bone mass by Wnt signaling
V Krishnan et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)