4.8 Editorial Material

LIS1 cracks open dynein

Journal

NATURE CELL BIOLOGY
Volume 22, Issue 5, Pages 515-517

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/s41556-020-0500-5

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Funding

  1. NIGMS NIH HHS [R35 GM124889] Funding Source: Medline

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Active transport along microtubules by molecular motors is a crucial cellular process that is disrupted in human diseases. Single-molecule studies from three independent groups reveal a new molecular mechanism for how cells control the activity of the complex microtubule motor cytoplasmic dynein via the neurodevelopmental protein LIS1.

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