4.8 Article

Superior field performance of waxy corn engineered using CRISPR-Cas9

Journal

NATURE BIOTECHNOLOGY
Volume 38, Issue 5, Pages 579-+

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41587-020-0444-0

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Funding

  1. Corteva Agriscience, a for-profit agricultural technology company, as part of its research and development program

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We created waxy corn hybrids by CRISPR-Cas9 editing of a waxy allele in 12 elite inbred maize lines, a process that was more than a year faster than conventional trait introgression using backcrossing and marker-assisted selection. Field trials at 25 locations showed that CRISPR-waxy hybrids were agronomically superior to introgressed hybrids, producing on average 5.5 bushels per acre higher yield. Gene-edited waxy corn lines have higher yields in field trials than hybrids produced by traditional trait introgression.

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