Cardenolide and pregnatriene compounds from the roots of Nerium oleander

Cardenolide and pregnatriene compounds were isolated from the chloroform fraction of the 95% aqueous ethanolic extract of dried roots of Nerium oleander. The stereochemical structure of the cardenolide and pregnatriene compounds was determined to be 3 beta-O-(D-diginosyl)-14 beta-hydroxy card-20(22)-enolide and 12 beta-hydroxy pregna-4,6,16-triene-3,20-dione using spectroscopic methods including IR, HRMS and NMR spectroscopy.

Automated summary

Cardenolide and pregnatriene compounds were isolated from the chloroform fraction of the 95% aqueous ethanolic extract of dried roots of Nerium oleander. The stereochemical structure of these compounds was determined using spectroscopic methods including IR, HRMS and NMR spectroscopy.