4.6 Review

Methods to Enhance the Metabolic Stability of Peptide-Based PET Radiopharmaceuticals

Related references

Note: Only part of the references are listed.
Review Medicine, General & Internal

Neuroendocrine Tumor Therapy with Lutetium-177: A Literature Review

Muhammad Haisum Maqsood et al.

CUREUS JOURNAL OF MEDICAL SCIENCE (2019)

Article Biochemistry & Molecular Biology

Improving oral bioavailability of cyclic peptides by N-methylation

Andreas F. B. Raeder et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2018)

Review Biochemical Research Methods

PET radiometals for antibody labeling

Eduardo Aluicio-Sarduy et al.

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

An Overview of PET Radiochemistry, Part 2: Radiometals

Marie Brandt et al.

JOURNAL OF NUCLEAR MEDICINE (2018)

Article Biochemistry & Molecular Biology

Design of cyclic and d-amino acids containing peptidomimetics for inhibition of protein-protein interactions of HER2-HER3

Sandeep Pallerla et al.

JOURNAL OF PEPTIDE SCIENCE (2018)

Article Multidisciplinary Sciences

Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB

Michael Garton et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Biochemistry & Molecular Biology

Amide Bond Activation of Biological Molecules

Sriram Mahesh et al.

MOLECULES (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

Approaches to improve metabolic stability of a statine-based GRP receptor antagonist

Ilinca Popp et al.

NUCLEAR MEDICINE AND BIOLOGY (2017)

Review Biotechnology & Applied Microbiology

TheranosticsTheranostics in nuclear medicine practice

Anna Yordanova et al.

ONCOTARGETS AND THERAPY (2017)

Article Multidisciplinary Sciences

A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

Tobias G. Kapp et al.

SCIENTIFIC REPORTS (2017)

Review Pharmacology & Pharmacy

Peptidomimetic therapeutics: scientific approaches and opportunities

Nir Qvit et al.

DRUG DISCOVERY TODAY (2017)

Article Biochemistry & Molecular Biology

A Potent D-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo

Maruti Uppalapati et al.

ACS CHEMICAL BIOLOGY (2016)

Review Biochemistry & Molecular Biology

Molecular imaging probes derived from natural peptides

C. L. Charron et al.

NATURAL PRODUCT REPORTS (2016)

News Item Biotechnology & Applied Microbiology

FDA approvals for the first 6 months of 2016

Asher Mullard

NATURE REVIEWS DRUG DISCOVERY (2016)

Article Chemistry, Organic

Influence of length and flexibility of spacers on the binding affinity of divalent ligands

Susanne Liese et al.

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2015)

Article Biochemical Research Methods

Improving the stability of peptidic radiotracers by the introduction of artificial scaffolds: which structure element is most useful?

Lisa Bacher et al.

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS (2015)

Article Radiology, Nuclear Medicine & Medical Imaging

The Effect of Bi-Terminal PEGylation of an Integrin αvβ6-Targeted 18F Peptide on Pharmacokinetics and Tumor Uptake

Sven H. Hausner et al.

JOURNAL OF NUCLEAR MEDICINE (2015)

Review Biochemistry & Molecular Biology

Methods to Increase the Metabolic Stability of 18F-Radiotracers

Manuela Kuchar et al.

MOLECULES (2015)

Article Chemistry, Medicinal

F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging

Hye Lan Kim et al.

ACS MEDICINAL CHEMISTRY LETTERS (2015)

Article Chemistry, Multidisciplinary

A D-Amino Acid at the N-Terminus of a Protein Abrogates Its Degradation by the N-End Rule Pathway

Amy E. Rabideau et al.

ACS CENTRAL SCIENCE (2015)

Review Pharmacology & Pharmacy

Early Engineering Approaches to Improve Peptide Developability and Manufacturability

Jennifer L. Furman et al.

AAPS JOURNAL (2015)

Article Chemistry, Multidisciplinary

Efficient Regioselective Ring Opening of Activated Aziridine-2-Carboxylates with [18F] Fluoride

Christina Schjoeth-Eskesen et al.

CHEMISTRYOPEN (2015)

Review Chemistry, Multidisciplinary

A Philosophy for CNS Radiotracer Design

Genevieve C. Van de Bittner et al.

ACCOUNTS OF CHEMICAL RESEARCH (2014)

Review Chemistry, Multidisciplinary

Matching chelators to radiometals for radiopharmaceuticals

Eric W. Price et al.

CHEMICAL SOCIETY REVIEWS (2014)

Review Biochemistry & Molecular Biology

Effects of pharmaceutical PEGylation on drug metabolism and its clinical concerns

Xingwang Zhang et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2014)

Review Biochemistry & Molecular Biology

Therapeutic radionuclides in nuclear medicine: current and future prospects

Chai-Hong Yeong et al.

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2014)

Article Radiology, Nuclear Medicine & Medical Imaging

PEG spacers of different length influence the biological profile of bombesin-based radiolabeled antagonists

Mazen Jamous et al.

NUCLEAR MEDICINE AND BIOLOGY (2014)

Article Biochemistry & Molecular Biology

DrugBank 4.0: shedding new light on drug metabolism

Vivian Law et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

Functional consequences of retro-inverso isomerization of a miniature protein inhibitor of the p53-MDM2 interaction

Chong Li et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2013)

Review Pharmacology & Pharmacy

Pharmacokinetics and Pharmacokinetic-Pharmacodynamic Correlations of Therapeutic Peptides

Lei Diao et al.

CLINICAL PHARMACOKINETICS (2013)

Article Chemistry, Medicinal

Labeling Strategies of Peptides with 18F for Positron Emission Tomography

D. E. Olberg et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2012)

Article Pharmacology & Pharmacy

Metabolism of small antimicrobial β2,2-amino acid derivatives by murine liver microsomes

Terkel Hansen et al.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS (2012)

Article Biochemistry & Molecular Biology

Synthesis of anticancer heptapeptides containing a unique lipophilic ß2,2-amino acid building block

Veronika Torfoss et al.

JOURNAL OF PEPTIDE SCIENCE (2012)

Review Medicine, Research & Experimental

Radiolabeled Peptides: Valuable Tools for the Detection and Treatment of Cancer

M. Fani et al.

THERANOSTICS (2012)

Article Chemistry, Inorganic & Nuclear

Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions

V. Carroll et al.

RADIOCHIMICA ACTA (2012)

Review Pharmacology & Pharmacy

Prodrugs for improving tumor targetability and efficiency

Rubi Mahato et al.

ADVANCED DRUG DELIVERY REVIEWS (2011)

Review Biochemistry & Molecular Biology

Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics

Rob M. J. Liskamp et al.

CHEMBIOCHEM (2011)

Article Biochemistry & Molecular Biology

Metabolic Stability of Peptidomimetics: N-Methyl and Aza Heptapeptide Analogs of a PKB/Akt Inhibitor

Yftah Tal-Gan et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2011)

Article Biochemistry & Molecular Biology

Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface

Emilia Antolikova et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

Tina R. White et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Radiology, Nuclear Medicine & Medical Imaging

PEGylation of 99mTc-labeled bombesin analogues improves their pharmacokinetic properties

Simone Daepp et al.

NUCLEAR MEDICINE AND BIOLOGY (2011)

Article Radiology, Nuclear Medicine & Medical Imaging

Mini-PEG spacering of VAP-1-targeting Ga-68-DOTAVAP-P1 peptide improves PET imaging of inflammation

Anu Autio et al.

EJNMMI RESEARCH (2011)

Article Biochemistry & Molecular Biology

Systematic Analysis of Helical Protein Interfaces Reveals Targets for Synthetic Inhibitors

Andrea L. Jochim et al.

ACS CHEMICAL BIOLOGY (2010)

Review Pharmacology & Pharmacy

Synthetic therapeutic peptides: science and market

Patrick Vlieghe et al.

DRUG DISCOVERY TODAY (2010)

Article Biochemistry & Molecular Biology

Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry

Chong Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Monodispersed DOTA-PEG-Conjugated Anti-TAG-72 Diabody Has Low Kidney Uptake and High Tumor-to-Blood Ratios Resulting in Improved 64Cu PET

Lin Li et al.

JOURNAL OF NUCLEAR MEDICINE (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Fluorine-18 radiopharmaceuticals beyond [18F]FDG for use in oncology and neurosciences

H. H. Coenen et al.

NUCLEAR MEDICINE AND BIOLOGY (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

68Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin αvβ3 PET imaging

Zhaofei Liu et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2009)

Article Medicine, Research & Experimental

Improving Tumor-Targeting Capability and Pharmacokinetics of Tc-99m-Labeled Cyclic RGD Dimers with PEG(4) Linkers

Lijun Wang et al.

MOLECULAR PHARMACEUTICS (2009)

Review Biochemical Research Methods

Molecular imaging targeting peptide receptors

Margret Schottelius et al.

METHODS (2009)

Review Chemistry, Multidisciplinary

Protein Design with L- and D-alpha-Amino Acid Structures as the Alphabet

Susheel Durani

ACCOUNTS OF CHEMICAL RESEARCH (2008)

Article Biochemical Research Methods

Influence of the Molecular Charge on the Biodistribution of Bombesin Analogues Labeled with the [99mTc(CO)3]-Core

Elisa Garcia Garayoa et al.

BIOCONJUGATE CHEMISTRY (2008)

Article Radiology, Nuclear Medicine & Medical Imaging

Macrocyclic chelator-coupled gastrin-based radiopharmaceuticals for targeting of gastrin receptor-expressing tumours

Stephan Good et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2008)

Article Radiology, Nuclear Medicine & Medical Imaging

18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2):: synthesis and microPET imaging of αvβ3 integrin expression

Zhanhong Wu et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2007)

Article Radiology, Nuclear Medicine & Medical Imaging

DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours

Hanwen Zhang et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2007)

Review Oncology

Positron emission tomography in oncology: A review

K. A. Wood et al.

CLINICAL ONCOLOGY (2007)

Article Chemistry, Medicinal

Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics

Luca Gentilucci et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

Article Biochemical Research Methods

Influence of different spacers on the biological profile of a DOTA-somatostatin analogue

Patricia Antunes et al.

BIOCONJUGATE CHEMISTRY (2007)

Article Radiology, Nuclear Medicine & Medical Imaging

Chemical and biological characterization of new Re(CO)(3)/[(TC)-T-99m](CO)(3) bombesin analogues

Elisa Garcia Garayoa et al.

NUCLEAR MEDICINE AND BIOLOGY (2007)

Article Radiology, Nuclear Medicine & Medical Imaging

Effects of linker variation on the in vitro and in vivo characteristics of an In-111-labeled RGD peptide

Ingrid Dijkgraaf et al.

NUCLEAR MEDICINE AND BIOLOGY (2007)

Review Chemistry, Multidisciplinary

Synthesis and properties of cyclopropane-derived peptidomimetics

Andreas Reichelt et al.

ACCOUNTS OF CHEMICAL RESEARCH (2006)

Review Polymer Science

Polymer-drug conjugates: Progress in polymeric prodrugs

Jayant Khandare et al.

PROGRESS IN POLYMER SCIENCE (2006)

Review Biochemistry & Molecular Biology

Strategies to improve plasma half life time of peptide and protein drugs

M. Werle et al.

AMINO ACIDS (2006)

Review Pharmacology & Pharmacy

PEGylation, successful approach to drug delivery

FM Veronese et al.

DRUG DISCOVERY TODAY (2005)

Article Biochemistry & Molecular Biology

The effect of cyclization on the enzymatic degradation of herpes simplex virus glycoprotein D derived epitope peptide

R Tugyi et al.

JOURNAL OF PEPTIDE SCIENCE (2005)

Review Chemistry, Medicinal

Protein, peptide and non-peptide drug PEGylation for therapeutic application

G Pasut et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2004)

Article Biochemistry & Molecular Biology

Peptide transformation leading to peptide-peptidosulfonamide hybrids and oligo peptidosulfonamides

Rob M. J. Liskamp et al.

MOLECULAR DIVERSITY (2004)

Article Chemistry, Organic

Synthesis of cyclic peptidosulfonamides by ring-closing metathesis

AJ Brouwer et al.

JOURNAL OF ORGANIC CHEMISTRY (2004)

Review Endocrinology & Metabolism

Peptide receptors as molecular targets for cancer diagnosis and therapy

JC Reubi

ENDOCRINE REVIEWS (2003)

Article Chemistry, Organic

HIV-1 protease: mechanism and drug discovery

A Brik et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2003)

Review Biochemistry & Molecular Biology

Structure and function of RGD peptides involved in bone biology

P Schaffner et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2003)

Review Chemistry, Multidisciplinary

Serine protease mechanism and specificity

L Hedstrom

CHEMICAL REVIEWS (2002)

Article Chemistry, Organic

A one-pot synthesis of 3-amino-3-arylpropionic acids

CYK Tan et al.

TETRAHEDRON (2002)

Article Biochemical Research Methods

Positron emission tomography: the conceptual idea using a multidisciplinary approach

AMJ Paans et al.

METHODS (2002)

Article Radiology, Nuclear Medicine & Medical Imaging

Rapid solid phase synthesis and biodistribution of 18F-labelled linear peptides

JL Sutcliffe-Goulden et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2002)

Article Biochemistry & Molecular Biology

Y-90-DOTA-D-Phe(1)-Try(3)-octreotide in therapy of neuroendocrine malignancies

G Paganelli et al.

BIOPOLYMERS (2002)

Review Biochemical Research Methods

Bifunctional chelators for therapeutic lanthanide radiopharmaceuticals

S Liu et al.

BIOCONJUGATE CHEMISTRY (2001)

Article Radiology, Nuclear Medicine & Medical Imaging

Biologically stable [18F]-labeled benzylfluoride derivatives

Y Magata et al.

NUCLEAR MEDICINE AND BIOLOGY (2000)