Journal
MOLECULAR CANCER
Volume 19, Issue 1, Pages -Publisher
BMC
DOI: 10.1186/s12943-020-01162-0
Keywords
Cancer; Drug resistance; Long non-coding RNAs
Categories
Funding
- Science and Technology Foundation of Shenzhen [JCYJ20170412155231633, JCYJ20180305164128430, GJHZ2018092817160, JCYJ20180301170047864, GJHZ20180928171802117]
- Shenzhen Economic and Information Committee Innovation Chain and Industry Chain integration special support plan project [20180225112449943]
- National Natural Science Foundation of China [81802749]
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Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various mechanisms. Over the last decade, it has been reported that 1ong noncoding RNAs (lncRNAs) can mediate carcinogenesis and drug resistance/sensitivity in cancer cells. This article reviews, in detail, recent studies regarding the roles of lncRNAs in mediating drug resistance.
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