Journal
MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES
Volume 30, Issue 6, Pages 363-368Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/13645706.2020.1739711
Keywords
Laparoscopic surgery; haemostasis; self-assembled peptides
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This study analyzed the feasibility of a new synthetic haemostatic device in laparoscopic colorectal surgery. The results demonstrated that the haemostatic device was easy to use, safe and effective in surgery, with no post-operative complications observed.
Introduction: Haemorrhage remains a major cause of morbidity and death in all surgical specialties. The aim of this study was to analyse the feasibility of PuraStat(R), a new synthetic haemostatic device, made of self-assembling peptides in laparoscopic colorectal surgery. Material and methods: This was a prospective observational non-randomised study. Consecutive patients undergoing laparoscopic colorectal surgery were enrolled. Inclusion criterion was the need employ a secondary method of haemostasis when traditional methods such as conventional pressure or utilization of energy devices to control the bleeding were either insufficient or not recommended. Results: Twenty patients were enrolled. The mean time to apply the product was 40 secs (+/- 17 secs), whereas the mean time to achieve haemostasis was 17.5 secs (+/- 3.5 secs). There were no post-operative complications in this cohort of 20 patients. Mean operative time overall was 185 mins (+/- 45.2 mins). None of the patients experienced delayed post-operative bleeding and the mean hospital stay was five days (+/- 3,4). Conclusions: We demonstrated that PuraStat(R) can be easily used in laparoscopic surgery and it is a safe, effective haemostatic agent. This is a feasibility study and additional controlled studies would be useful in the future.
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