4.6 Article

Report on G4-Med, a Geant4 benchmarking system for medical physics applications developed by the Geant4 Medical Simulation Benchmarking Group

Journal

MEDICAL PHYSICS
Volume 48, Issue 1, Pages 19-56

Publisher

WILEY
DOI: 10.1002/mp.14226

Keywords

benchmarking; Geant4; medical physics; Monte Carlo

Funding

  1. Australian Government Research Training Program Scholarship
  2. Spanish Ministry of Economy and Competitiveness [FPA2016-77689-C2-1-R]
  3. NIH [U24CA215123]
  4. Australian Research Council [ARC DP170100967, DP170102423]
  5. CNRS through the IN2P3/MOVI Master Project
  6. CNRS through France-Greece funding scheme [PICS 8235]
  7. European Space Agency [4000126645/19/NL/BW]
  8. Susan G Komen Foundation [IIR13262248]
  9. Australian National Computing Infrastructure (NCI), through the NCMAS 2020 grant scheme

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Geant4 is a widely used Monte Carlo code in medical physics with various applications, and it is essential to have a system for benchmarking and regression testing. G4-Med was developed to address these needs and currently includes 18 tests covering a range of physics processes and models typical in medical physics applications. Results from benchmarking Geant4 10.5 against reference data show good agreement for electromagnetic physics constructor and adequate description for hadron therapy with the QGSP_BIC_HP physics list. Future work should focus on expanding benchmarking to other physical quantities and application scenarios in medical physics.
Background Geant4 is a Monte Carlo code extensively used in medical physics for a wide range of applications, such as dosimetry, micro- and nanodosimetry, imaging, radiation protection, and nuclear medicine. Geant4 is continuously evolving, so it is crucial to have a system that benchmarks this Monte Carlo code for medical physics against reference data and to perform regression testing. Aims To respond to these needs, we developed G4-Med, a benchmarking and regression testing system of Geant4 for medical physics. Materials and Methods G4-Med currently includes 18 tests. They range from the benchmarking of fundamental physics quantities to the testing of Monte Carlo simulation setups typical of medical physics applications. Both electromagnetic and hadronic physics processes and models within the prebuilt Geant4 physics lists are tested. The tests included in G4-Med are executed on the CERN computing infrastructure via the use of the geant-val web application, developed at CERN for Geant4 testing. The physical observables can be compared to reference data for benchmarking and to results of previous Geant4 versions for regression testing purposes. Results This paper describes the tests included in G4-Med and shows the results derived from the benchmarking of Geant4 10.5 against reference data. Discussion Our results indicate that the Geant4 electromagnetic physics constructor G4EmStandardPhysics_option4 gives a good agreement with the reference data for all the tests. The QGSP_BIC_HP physics list provided an overall adequate description of the physics involved in hadron therapy, including proton and carbon ion therapy. New tests should be included in the next stage of the project to extend the benchmarking to other physical quantities and application scenarios of interest for medical physics. Conclusion The results presented and discussed in this paper will aid users in tailoring physics lists to their particular application.

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