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NECT Is Next: Implementing the New Drug Combination Therapy for Trypanosoma brucei gambiense Sleeping Sickness

Oliver Yun et al.

PLOS NEGLECTED TROPICAL DISEASES (2010)

Review Biochemistry & Molecular Biology

Pentavalent Antimonials: New Perspectives for Old Drugs

Frederic Frezard et al.

MOLECULES (2009)

Review Chemistry, Medicinal

Marine Antimalarials

Ernesto Fattorusso et al.

MARINE DRUGS (2009)

Review Pharmacology & Pharmacy

Pharmacokinetic and Toxicological Profile of Artemisinin Compounds: An Update

Bikash Medhi et al.

PHARMACOLOGY (2009)

Review Parasitology

Imaging Leishmania development in their host cells

Thierry Lang et al.

TRENDS IN PARASITOLOGY (2009)

Review Parasitology

Reporter genes facilitating discovery of drugs targeting protozoan parasites

Anuradha Dube et al.

TRENDS IN PARASITOLOGY (2009)

Review Medicine, General & Internal

Artemisinin-based combination therapy for treating uncomplicated malaria

David Sinclair et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2009)

Article Plant Sciences

Kinetic studies and bioactivity of potential manzamine prodrugs

Abbas Gholipour Shilabin et al.

JOURNAL OF NATURAL PRODUCTS (2008)

Article Biochemistry & Molecular Biology

Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes

Natasha Sienkiewicz et al.

MOLECULAR MICROBIOLOGY (2008)

Article Multidisciplinary Sciences

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

Shane R. Wilkinson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Public, Environmental & Occupational Health

Performance and reliability of the SYBR Green I based assay for the routine monitoring or susceptibility of Plasmodium falciparum clinical associates

Marie Ange Rason et al.

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2008)

Review Infectious Diseases

The Natural Progression of Gambiense Sleeping Sickness: What Is the Evidence?

Francesco Checchi et al.

PLOS NEGLECTED TROPICAL DISEASES (2008)

Article Infectious Diseases

Macrophage and T-Cell Gene Expression in a Model of Early Infection with the Protozoan Leishmania chagasi

Nicholas A. Ettinger et al.

PLOS NEGLECTED TROPICAL DISEASES (2008)

Review Pharmacology & Pharmacy

Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

M. P. Barrett et al.

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Review Parasitology

Target assessment for antiparasitic drug discovery

Julie A. Frearson et al.

TRENDS IN PARASITOLOGY (2007)

Article Medicine, General & Internal

Injectable paromomycin for visceral leishmaniasis in India

Shyam Sundar et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Immunology

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites

Mallika Imwong et al.

JOURNAL OF INFECTIOUS DISEASES (2007)

Review Oncology

Antimalarial drug toxicity: A review

Hussien O. Alkadi

CHEMOTHERAPY (2007)

Review Infectious Diseases

Cutaneous leishmaniasis

Richard Reithinger et al.

LANCET INFECTIOUS DISEASES (2007)

Review Biochemistry & Molecular Biology

S-adenosylmethionine in protozoan parasites: Functions, synthesis and regulation

Rosa M. Reguera et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2007)

Review Pharmacology & Pharmacy

Targeting atypical trypanosomatid DNA topoisomerase I

Rafael Balana-Fouce et al.

DRUG DISCOVERY TODAY (2006)

Article Toxicology

Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis)

Jose A. Castro et al.

HUMAN & EXPERIMENTAL TOXICOLOGY (2006)

Article Biochemistry & Molecular Biology

Antimalarial potential of xestoquinone, a protein kinase inhibitor isolated from a Vanuatu marine sponge Xestospongia sp.

Dominique Laurent et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2006)

Review Biochemistry & Molecular Biology

Regulation of ornithine decarboxylase

Anthony E. Pegg

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Microbiology

New approach for high-throughput screening of drug activity on Plasmodium liver stages

A Gego et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)

Article Biochemistry & Molecular Biology

DNA binding properties of 9-substituted harmine derivatives

RH Cao et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Article Biochemistry & Molecular Biology

High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase

J Baldwin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Biochemical Research Methods

Targeting the hemozoin synthesis pathway for new antimalarial drug discovery:: Technologies for in vitro β-hematin formation assay

BL Tekwani et al.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2005)

Article Microbiology

Possible mechanism of miltefosine-mediated death of Leishmania donovani

NK Verma et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Article Biochemistry & Molecular Biology

RNA interference of Trypanosoma brucei topoisomerase IB:: both subunits are essential

RP Bakshi et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2004)

Article Microbiology

Novel, rapid, and inexpensive cell-based quantification of antimalarial drug efficacy

TN Bennett et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Article Biochemical Research Methods

Comparison of noninvasive fluorescent and bioluminescent small animal optical imaging

G Choy et al.

BIOTECHNIQUES (2003)

Article Parasitology

Eflornithine for the treatment of human African trypanosomiasis

C Burri et al.

PARASITOLOGY RESEARCH (2003)

Article Biochemistry & Molecular Biology

Turnover of trypanosomal ornithine decarboxylases

L Persson et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2003)

Article Biochemistry & Molecular Biology

Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites

HP Price et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Infectious Diseases

Post-kala-azar dermal leishmaniasis

EE Zijistra et al.

LANCET INFECTIOUS DISEASES (2003)

Article Parasitology

Artemisinin: mechanisms of action, resistance and toxicity

SR Meshnick

INTERNATIONAL JOURNAL FOR PARASITOLOGY (2002)

Article Biochemistry & Molecular Biology

Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei

A Pal et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2002)

Article Infectious Diseases

Amphotericin B nephrotoxicity

G Deray

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2002)

Review Chemistry, Medicinal

Polyamine Metabolism as Chemotherapeutic Target in Protozoan Parasites

C. J. Bacchi et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2002)

Review Oncology

Marine organisms as a source of new anticancer agents

Gilberto Schwartsmann et al.

LANCET ONCOLOGY (2001)

Article Biochemistry & Molecular Biology

Novel intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani

P Shaked-Mishan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Microbiology

In vivo antimalarial activity of the beta-carboline alkaloid manzamine A

KKH Ang et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)

Article Biochemistry & Molecular Biology

Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes

A Misslitz et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2000)