Journal
CHEMICAL ENGINEERING JOURNAL
Volume 296, Issue -, Pages 56-70Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.cej.2016.02.119
Keywords
Flow chemistry; Chemical reaction engineering; Microreactors; Process design; Reactor scale-up
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Flow chemistry has been proposed in modern organic chemistry as a mean for process intensification, to improve the control over reaction performance and to achieve higher yield. However, many open issues can be evidenced regarding the true possibility of scale-up, as well as currently lacking information for process design and economical evaluation. This review proposes some recent examples of flow synthesis deepening in particular the scale-up and engineering issues. Required information is evidenced, as well as some transport and kinetic data required for the practical implementation of the results. (C) 2016 Elsevier B.V. All rights reserved.
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