4.7 Article

Modeling polyhydroxyalkanoate (PHA) production in a newly developed aerobic dynamic discharge (ADD) culture enrichment process

Journal

CHEMICAL ENGINEERING JOURNAL
Volume 298, Issue -, Pages 36-43

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.cej.2016.03.133

Keywords

Polyhydroxyalkanoate (PHA); Aerobic dynamic discharge (ADD); Modeling; Physical selective pressure; Mixed microbial cultures (MMCs)

Funding

  1. National Natural Science Foundation of China [51578183]
  2. program for New Century Excellent Talents in University [NCET-12-0156]
  3. open Project of the State Key Laboratory of Urban Water Resource and Environment (Harbin Institute of Technology) [2015DX10]

Ask authors/readers for more resources

This study presents a mathematical model of an aerobic dynamic discharge (ADD) process developed to improve the selection of efficient mixed PHA accumulation cultures. Conventional aerobic dynamic feeding (ADF) mode modeling is extended to include the ADD's physical selective pressure to favor the accumulation of PHAs accumulating bacteria. The model includes the uptake substrate, PHA degradation and synthesis and PHA inhibition. Good fit between experimental data and simulations shows that the model is able to account for the dynamic processes and thereby to simulate the selection phase and transition to the pseudo-steady state of PHA production phase. Two variables ((V-s)=(feast_end)(min) and phi-value), introduced to quantify the influence of the physical selective pressure on the PHA accumulating ability of mixed microbial cultures (MMCs), can be used for process control. (C) 2016 Elsevier B.V. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available