4.7 Article

BODIPY-containing nanoscale metal-organic frameworks for photodynamic therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 31, Pages 5402-5405

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc01048b

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Funding

  1. National Natural Science Foundation of China [21401188, 51522307]

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BODIPY-immobilized zirconium-based nanoscale metal-organic frameworks (MOFs), named UiO-PDT, have been synthesized through solvent-assisted ligand exchange using UiO-typed MOFs and pre-designed BODIPY ligands for the first time. The UiO-PDT nanocrystal has been proved to possess good biocompatibility and highly efficient generation of singlet oxygen, which could kill the cancer cells effectively.

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