4.7 Article

Cobalt-catalyzed chelation assisted C-H allylation of aromatic amides with unactivated olefins

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 66, Pages 10129-10132

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc05330k

Keywords

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Funding

  1. Monbusho (The Ministry of Education, Culture, Sports, Science and Technology) [22105001]
  2. JST Strategic Basic Research Programs Advanced Catalytic Transformation Program for Carbon Utilization (ACT-C) from the Japan Science and Technology Agency [52571]
  3. JSPS
  4. Grants-in-Aid for Scientific Research [22105001] Funding Source: KAKEN

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The cobalt-catalyzed chelation assisted ortho C-H allylation of aromatic amides with unactivated aliphatic alkenes is reported. The reaction proceeds in air under mild reaction conditions, providing allylated products in good to excellent yields with high E-selectivities. This operationally simple method shows a high functional group tolerance.

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