4.7 Article

A long lifetime switch-on iridium(III) chemosensor for the visualization of cysteine in live zebrafish

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 24, Pages 4450-4453

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc01008c

Keywords

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Funding

  1. Hong Kong Baptist University [FRG2/14-15/004]
  2. Health and Medical Research Fund [HMRF/14130522]
  3. Research Grants Council [HKBU/201811, HKBU/204612, HKBU/201913]
  4. French Agence Nationale de la Recherche/Research Grants Council Joint Research Scheme [A-HKBU201/12, ANR-12-IS07-0001]
  5. National Natural Science Foundation of China [21575121]
  6. Guangdong Province Natural Science Foundation [2015A030313816]
  7. Hong Kong Baptist University
  8. Interdisciplinary Research Matching Scheme [RC-IRMS/14-15/06]
  9. Inter-institutional Collaborative Research Scheme [RC-ICRS/15-16/02A]
  10. Macao SAR [098/2014/A2, 007/2014/AMJ]
  11. University of Macau [MYRG091(Y3-L2)-ICMS12-LCH, MYRG2015-00137-ICMS-QRCM, MRG023/LCH/2013/ICMS, MRG044/LCH/2015/ICMS]
  12. Science and Technology Development Fund

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A long lifetime iridium(III) complex chemosensor 1 for cysteine detection has been synthesized. The luminescence signal of 1 could be recognized in strongly fluorescent media through time-resolved emission spectroscopy (TRES). The detection of cysteine in a living zebrafish was demonstrated.

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