Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 20, Pages 3959-3961Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc01014h
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Funding
- Beijing Key Laboratory of Science and Technology Fund [Z141102004414034]
- Mega-Project of Science Research [2012ZX10004502]
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Herein, we describe a novel approach for the rapid diagnosis of human breast carcinoma MCF-7 cells with a detection limit of 100 cells mL(-1). In our strategy, the MCF-7 cells are specially recognized by mucin 1 protein (MUC-1) aptamer-functionalized gold nanorods (GNRs) through specific interactions, whose signals are simply read out by its unique localized surface plasmon resonance (LSPR) spectra.
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