4.6 Article

The first imported case of extensively drug-resistant Salmonella enterica serotype Typhi infection in Taiwan and the antimicrobial therapy

Journal

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
Volume 54, Issue 4, Pages 740-744

Publisher

ELSEVIER TAIWAN
DOI: 10.1016/j.jmii.2020.03.017

Keywords

Typhoid fever; Salmonella enterica serovar Typhi; Drug resistance; Travel medicine; Ceftriaxone; Fluoroquinolones

Funding

  1. Ministry of Health and Wel-fare, Taiwan [MOHW108-CDC-C-315-122129]

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The first imported case of XDR typhoid fever in Taiwan is linked to a bacterial strain closely related to Pakistan. Treatment for XDR typhoid fever should involve a combination of meropenem and an antimicrobial with intracellular activity against Salmonella.
The first imported case of XDR typhoid fever in Taiwan contracted with a bacterial strain, which was most closely related to the bla(CTX-M-15)-carrying strains linked to Pakistan. Meropenem, in combination with an antimicrobial with intracellular activity against Salmonella, should be used for the treatment of XDR typhoid fever. Copyright (C) 2020, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC.

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