4.7 Article

Programmed photosensitizer conjugated supramolecular nanocarriers with dual targeting ability for enhanced photodynamic therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 80, Pages 11935-11938

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc06439f

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Funding

  1. National Natural Science Foundation of China [51303154, 51573160, 21574114, 51273177]
  2. Key Science Technology Innovation Team of Zhejiang Province [2013TD02]
  3. Fundamental Research Funds for Central Universities [2016QNA4033]

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A programmed supramolecular nanocarrier was developed for multistage targeted photodynamic therapy. This smart nanocarrier exhibited enhanced cellular uptake and controlled mitochondria targeting, as well as an excellent photodynamic therapeutic effect after light irradiation.

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