4.7 Article

A TICT-based fluorescent probe for rapid and specific detection of hydrogen sulfide and its bio-imaging applications

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 38, Pages 6415-6418

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc00966b

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Funding

  1. NSFC [21172063, 21472067, 21502067]
  2. Natural Science Foundation of Shandong Province, China [ZR2014BP001]
  3. Taishan Scholar Foundation [TS 201511041]
  4. University of Jinan

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By blocking the intramolecular twisted internal charge transfer (TICT) process, we designed and sythesized the first TICT-based fluorescent probe for hydrogen sulfide. The new probe exhibits high selectivity, good membrane-permeability and is suitable for visualization of exogenous and endogenous hydrogen sulfide in living cells.

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