4.7 Article

Trifluoromethyl nitrogen heterocycles: synthetic aspects and potential biological targets

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 15, Pages 3077-3094

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc09414c

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Recent advances regarding the synthetic chemistry of fluorinated aziridines, azetidines, pyrrolidines and their lactam/amino acid counterparts are presented. These heterocycles are of high importance both as building blocks for more complex structures and as active parts of medicinal chemistry-oriented compounds.

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