Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 65, Pages 10052-10055Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc04866h
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Funding
- National Basic Research Program of China (973 Program) [2012CB720600, 2012CB720603]
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Herein, we report two distinct G-quadruplex conformations of the same G-rich oligonucleotide, regulated by a small molecule. This is the first report in which both right-and left-handed G-quadruplex conformations have been obtained from the same sequence. We discriminated these two distinct conformations and investigated their kinetics and thermodynamics.
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