Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 18, Pages 3717-3720Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc09540a
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Funding
- NSFC [21175098, 21305104]
- National Nature Science Fund for distinguished Yong Scholars [21325521]
- Program of Shanghai Academic Research Leader [15XD1501600]
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pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.
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