Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 1, Pages 120-123Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc08317f
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Funding
- Walther Cancer Foundation Advancing Basic Cancer Research Grant
- NIH [GM059078, P30 CA016672, S10 OD010403]
- NATIONAL CANCER INSTITUTE [P30CA016672] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM059078] Funding Source: NIH RePORTER
- OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH [S10OD010403] Funding Source: NIH RePORTER
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Absorption of 808 nm laser light by liposomes containing a pH sensitive, near-infrared croconaine rotaxane dye increases dramatically in weak acid. A stealth liposome composition permits acid activated, photothermal heating and also acts as an effective nanoparticle probe for ratiometric photoacoustic imaging of acidic pH in deep sample locations, including a living mouse.
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