4.7 Article

Enantioselective sulfoxidation reaction catalyzed by a G-quadruplex DNA metalloenzyme

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 62, Pages 9644-9647

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc03016e

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Funding

  1. National Natural Science Foundation of China [21503229, 21227801]
  2. Natural Science Foundation of Liaoning Province [2015020700]

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Enantioselective sulfoxidation reaction is achieved for the first time by a DNA metalloenzyme assembled with the human telomeric G-quadruplex DNA and Cu(II)-4,4'-bimethyl-2,2'-bipyridine complex, and the mixed G-quadruplex architectures are responsible for the catalytic enantioselectivity and activity.

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