4.7 Article

New artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysis

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 38, Pages 6471-6474

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc02002j

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Funding

  1. National Natural Science Foundation of China [21236002]

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A new artificial fluoro-cofactor was developed for the replacement of natural cofactors NAD(P), exhibiting a high hydride transfer ability. More importantly, we established a new and fast screening method for the evaluation of the properties of artificial cofactors based on the fluorescence assay and visible color change.

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