4.7 Article

Nickel-catalysed cyclopropanation of electron-deficient alkenes with diiodomethane and diethylzinc

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 16, Pages 3372-3375

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc10296k

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Funding

  1. Institute of Chemical and Engineering Sciences (ICES), Agency for Science, Technology and Research (A*STAR), Singapore

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In the presence of a nickel catalyst, the cyclopropanation of electron-deficient alkenes with diiodomethane and diethylzinc is drastically accelerated. A wide range of cyclopropyl ketones, esters and amides can be accessed under these conditions.

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