4.7 Article

A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 1, Pages 164-166

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc07526b

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Funding

  1. University of Leeds
  2. Egyptian Government
  3. South Valley University
  4. Thailand Research Fund (TRF)
  5. Royal Golden Jubilee Program
  6. Center of Excellence for Innovation in Chemistry (PERCH-CIC)
  7. Mersin University
  8. Scientific and Technological Research Council of Turkey (TUBITAK), Commission on Higher Education, Ministry of Education
  9. Kasetsart University Research and Development Institute

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Palladium catalysed three component cascade process, involving coupling of 2-iodobenzoates, -benzaldehydes, or acetophenones with substituted allenes and ammonium tartrate as an ammonium surrogate, provides a novel and facile route to substituted functionalised isoquinolinones and isoquinolines in good yields.

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