4.7 Article

The Pauson-Khand reaction using alkynylboronic esters: solving a long-standing regioselectivity issue

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 60, Pages 9363-9366

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc04717c

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Funding

  1. Spanish Ministerio de Economia y Competividad [CTQ2013-43395-P]
  2. ACCIO [TECSPR13-1-0040]

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The first intermolecular Pauson-Khand reaction, conducted using internal alkynylboronic esters, allows the installation of the boronic ester moiety at the beta-position of the cyclopentenone with total regio- and stereoselectivity.

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