4.7 Article

Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation-borylation conditions

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 30, Pages 5289-5292

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc00536e

Keywords

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Funding

  1. European Research Council (FP7, ERC grant) [246785, H2020/2015-2020, 670668]
  2. EPSRC [EP/I038071/1, EP/L015366/1]
  3. Engineering and Physical Sciences Research Council [EP/I038071/1, EP/K03927X/1, 1652562] Funding Source: researchfish
  4. EPSRC [EP/K03927X/1] Funding Source: UKRI

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Hindered tertiary neopentyl glycol boronic esters can be prepared by using in situ lithiation-borylation of enantiopure secondary benzylic carbamates at -20 degrees C with full chirality transfer.

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