4.7 Article

Nanoplasmonic ruler to measure lipid vesicle deformation

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 1, Pages 76-79

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc06861d

Keywords

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Funding

  1. National Research Foundation [NRF-NRFF2011-01]
  2. National Medical Research Council [NMRC/CBRG/0005/2012]
  3. Czech Science Foundation [P205/12/G118]

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A nanoplasmonic ruler method is presented in order to measure the deformation of adsorbed, nm-scale lipid vesicles on solid supports. It is demonstrated that single adsorbed vesicles undergo greater deformation on silicon oxide over titanium oxide, offering direct experimental evidence to support membrane tension-based theoretical models of supported lipid bilayer formation.

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