Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 55, Pages 8537-8540Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc03193e
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Funding
- Welch Foundation [W-1640]
- National Science Foundation [CHE-0748483, CHE-1309978, CHE-1404911]
- Henry Dreyfus Teacher-Scholars Program
- Department of Education [P200A120241]
- University of Maryland
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The recognition of human growth hormone (hGH) by the synthetic host molecule cucurbit[7]uril (Q7) was predicted on the basis of its N-terminal phenylalanine. An aqueous-compatible resin with covalently immobilized Q7 groups was prepared and shown to recognize native insulin and hGH in simple and complex mixtures.
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