Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 20, Pages 3907-3910Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc09836j
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Funding
- National Natural Science Foundation of China [21374079]
- Program for New Century Excellent Talents in University [NCET-11-1063]
- 131 talents program of Tianjin
- Program for Prominent Young College Teachers of the Tianjin Educational Committee
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A fluorophore displaying aggregation-induced emission was introduced at the terminus of branched polyethylenimine (PEI). The formulated polyplex not only demonstrated an improved safety profile and preserved transfection activity but also importantly indicated that the uncomplexed naked DNA rather than the polyplexes translocated into the nucleus.
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