Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 7, Pages 1451-1454Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc08053c
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Funding
- Natural Sciences and Engineering Research Council of Canada
- NSERC CREATE-IDEM (Integrated Development of Extracellular Matrices) training program
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A direct, all-aqueous electrospinning method for fabricating degradable nanofibrous hydrogel networks is reported in which hydrazide and aldehyde-functionalized poly(oligoethylene glycol methacrylate) (POEGMA) polymers are simultaneously electrospun and cross-linked. The resulting networks are spatially well-defined, mechanically stable (both dry and wet), and offer extremely fast swelling responses, suggesting potential utility as smart hydrogels and tunable tissue engineering matrices.
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