4.7 Article

Dendrimer porphyrin-coated gold nanoshells for the synergistic combination of photodynamic and photothermal therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 6, Pages 1258-1261

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc09149g

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Funding

  1. Priority Research Centers Programs [2009-0093823]
  2. Active Polymer Center for Pattern Integration at Yonsei University [2007-0056091]
  3. Mid-Career Researcher Program through National Research Foundation of Korea (NRF) [2014R1A2A1A10051083]

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A dendrimer porphyrin (DP)-coated gold nanoshell (AuNS-DP) was prepared for the synergistic combination of photodyanmic and photothermal therapy. The resultant AuNS-DP successfully exhibited the generation of reactive oxygen species (ROS) as well as photothermal effect for the simultaneous application of photodynamic therapy (PDT) and photothermal therapy (PTT).

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