Related references
Note: Only part of the references are listed.MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells
Julia Merkenschlager et al.
BLOOD (2019)
Sustained B cell depletion by CD19-targeted CAR T cells is a highly effective treatment for murine lupus
Rita Kansal et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
The clinical utility of anti-double-stranded DNA antibodies and the challenges of their determination
Eckart Mummert et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2018)
Kidney Proximal Tubular TLR9 Exacerbates Ischemic Acute Kidney Injury
Sang Jun Han et al.
JOURNAL OF IMMUNOLOGY (2018)
Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus
Vincent Gies et al.
JCI INSIGHT (2018)
Self-dsDNA in the pathogenesis of systemic lupus erythematosus
Y. Bai et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2018)
Toll-like receptors in lupus nephritis
Satish Kumar Devarapu et al.
JOURNAL OF BIOMEDICAL SCIENCE (2018)
Tissue-Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells
Allison W. Roberts et al.
IMMUNITY (2017)
A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens
Vishal J. Sindhava et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Protective role of surface Toll-like receptor 9 expressing neutrophils in local inflammation during systemic inflammatory response syndrome in mice
Xiuping Meng et al.
MOLECULAR IMMUNOLOGY (2017)
Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice
Kevin M. Nickerson et al.
PLOS ONE (2017)
Lupus and proliferative nephritis are PAD4 independent in murine models
Rachael A. Gordon et al.
JCI INSIGHT (2017)
Trial Watch: Immunostimulation with Toll-like receptor agonists in cancer therapy
Kristina Iribarren et al.
ONCOIMMUNOLOGY (2016)
TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus
Lukas Bossaller et al.
JOURNAL OF IMMUNOLOGY (2016)
Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice
Osama M. El-Sayed et al.
JOURNAL OF VASCULAR SURGERY (2016)
Association between toll-like receptor polymorphisms and systemic lupus erythematosus: a meta-analysis update
Y. H. Lee et al.
LUPUS (2016)
Dendritic Cells in Systemic Lupus Erythematosus: From Pathogenic Players to Therapeutic Tools
Jared Klarquist et al.
MEDIATORS OF INFLAMMATION (2016)
Kidney Expression of Toll Like Receptors in Lupus Nephritis: Quantification and Clinicopathological Correlations
Fabrizio Conti et al.
MEDIATORS OF INFLAMMATION (2016)
A Plasmacytoid Dendritic Cells-Type I Interferon Axis Is Critically Implicated in the Pathogenesis of Systemic Lupus Erythematosus
Ji-Min Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses
Kerstin Nuendel et al.
JOURNAL OF IMMUNOLOGY (2015)
B Cell-Specific MHC Class II Deletion Reveals Multiple Nonredundant Roles for B Cell Antigen Presentation in Murine Lupus
Josephine R. Giles et al.
JOURNAL OF IMMUNOLOGY (2015)
RNA sensing by conventional dendritic cells is central to the development of lupus nephritis
Teja Celhar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Toll-Like Receptors in the Pathogenesis of Autoimmune Diseases
Akbar Mohammad Hosseini et al.
ADVANCED PHARMACEUTICAL BULLETIN (2015)
Associations between interleukin 1 polymorphisms and susceptibility to systemic lupus erythematosus: A meta-analysis
Gwan Gyu Song et al.
HUMAN IMMUNOLOGY (2014)
Maintenance treatment with the immunomodulator MGN1703, a Toll-like receptor 9 (TLR9) agonist, in patients with metastatic colorectal carcinoma and disease control after chemotherapy: a randomised, double-blind, placebo-controlled trial
Hans-Joachim Schmoll et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2014)
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
Clare L. Abram et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2014)
Opposing Impact of B Cell-Intrinsic TLR7 and TLR9 Signals on Autoantibody Repertoire and Systemic Inflammation
Shaun W. Jackson et al.
JOURNAL OF IMMUNOLOGY (2014)
Contributions of B cells to lupus pathogenesis
Allison Sang et al.
MOLECULAR IMMUNOLOGY (2014)
Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation
Julia Sieber et al.
ARTHRITIS RESEARCH & THERAPY (2014)
The role of activation-induced deaminase in Lupus Nephritis
Marilyn Diaz
AUTOIMMUNITY (2013)
Primary blood neutrophils express a functional cell surface Toll-like receptor 9
Dennis Lindau et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Endocytosis-free DNA sensing by cell surface TLR9 in neutrophils: Rapid defense with autoimmune risks
Kensuke Miyake et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Non-parallel recombination limits cre-loxP-based reporters as precise indicators of conditional genetic manipulation
Jing Liu et al.
GENESIS (2013)
Signals via the Adaptor MyD88 in B Cells and DCs Make Distinct and Synergistic Contributions to Immune Activation and Tissue Damage in Lupus
Lino L. Teichmann et al.
IMMUNITY (2013)
A critical role for interleukin-1β in the progression of autoimmune diseases
Ruijuan Zhao et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2013)
Cell-Specific TLR9 Trafficking in Primary APCs of Transgenic TLR9-GFP Mice
Ana M. Avalos et al.
JOURNAL OF IMMUNOLOGY (2013)
TLR9 Promotes Tolerance by Restricting Survival of Anergic Anti-DNA B Cells, Yet Is Also Required for Their Activation
Kevin M. Nickerson et al.
JOURNAL OF IMMUNOLOGY (2013)
An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing
Masahiro Onji et al.
NATURE COMMUNICATIONS (2013)
UNC93B1 mediates differential trafficking of endosomal TLRs
Bettina L. Lee et al.
ELIFE (2013)
TLR7 and TLR9 in SLE: when sensing self goes wrong
T. Celhar et al.
IMMUNOLOGIC RESEARCH (2012)
NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus
Allison M. Campbell et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking
Ryutaro Fukui et al.
IMMUNITY (2011)
Role for toll-like receptors in autoimmune disease: The example of systemic lupus erythematosus
Christophe Richez et al.
JOINT BONE SPINE (2011)
TLR9 in Peritoneal B-1b Cells Is Essential for Production of Protective Self-Reactive IgM To Control Th17 Cells and Severe Autoimmunity
Alexander D. Stoehr et al.
JOURNAL OF IMMUNOLOGY (2011)
Neutrophils in the pathogenesis and manifestations of SLE
Mariana J. Kaplan
NATURE REVIEWS RHEUMATOLOGY (2011)
Toll-like receptor driven B cell activation in the induction of systemic autoimmunity
Nathaniel M. Green et al.
SEMINARS IN IMMUNOLOGY (2011)
Monocyte and Macrophage Abnormalities in Systemic Lupus Erythematosus
Yi Li et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2010)
Dendritic Cells in Lupus Are Not Required for Activation of T and B Cells but Promote Their Expansion, Resulting in Tissue Damage
Lino L. Teichmann et al.
IMMUNITY (2010)
Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice
Marie-Laure Santiago-Raber et al.
JOURNAL OF AUTOIMMUNITY (2010)
TLR9 Regulates TLR7-and MyD88-Dependent Autoantibody Production and Disease in a Murine Model of Lupus
Kevin M. Nickerson et al.
JOURNAL OF IMMUNOLOGY (2010)
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
Ryutaro Fukui et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Yaa autoimmune phenotypes are conferred by overexpression of TLR7
Anna-Marie Fairhurst et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
You-Me Kim et al.
NATURE (2008)
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
Boyoun Park et al.
NATURE IMMUNOLOGY (2008)
The Immunological Genome Project: networks of gene expression in immune cells
Tracy S. P. Heng et al.
NATURE IMMUNOLOGY (2008)
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
Jonathan A. Deane et al.
IMMUNITY (2007)
Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen
Michele L. Caton et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
Melanie M. Brinkmann et al.
JOURNAL OF CELL BIOLOGY (2007)
Toll-like receptors in systemic autoimmune disease
Ann Marshak-Rothstein
NATURE REVIEWS IMMUNOLOGY (2006)
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
Sean R. Christensen et al.
IMMUNITY (2006)
Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE
Philipp Yu et al.
INTERNATIONAL IMMUNOLOGY (2006)
Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus
Aurelia Lartigue et al.
JOURNAL OF IMMUNOLOGY (2006)
Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells
SW Tas et al.
ANNALS OF THE RHEUMATIC DISEASES (2006)
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
K Honda et al.
NATURE (2005)
Toll-like receptors stimulate human neutrophil function
F Hayashi et al.
BLOOD (2003)
Genetic modifiers of systemic lupus erythematosus in FcγRIIB-/- mice
S Bolland et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
A Toll-like receptor recognizes bacterial DNA
H Hemmi et al.
NATURE (2000)