Related references
Note: Only part of the references are listed.Cell-cell contacts protect against t-BuOOH-induced cellular damage and ferroptosis in vitro
Christine Wenz et al.
ARCHIVES OF TOXICOLOGY (2019)
The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11
Tong Liu et al.
CANCER RESEARCH (2019)
Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes
Katarina Trajkovic et al.
PLOS ONE (2019)
Targeting Ferroptosis to Iron Out Cancer
Behrouz Hassannia et al.
CANCER CELL (2019)
The cystine/glutamate antiporter xCT is a key regulator of EphA2 S897 phosphorylation under glucose-limited conditions
Koji Teramoto et al.
CELLULAR SIGNALLING (2019)
The lysosome as a cellular centre for signalling, metabolism and quality control
Rosalie E. Lawrence et al.
NATURE CELL BIOLOGY (2019)
Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion
Jose Pedro Friedmann Angeli et al.
NATURE REVIEWS CANCER (2019)
Cell clustering mediated by the adhesion protein PVRL4 is necessary for α6β4 integrin-promoted ferroptosis resistance in matrix-detached cells
Caitlin W. Brown et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity
Xinxin Song et al.
CURRENT BIOLOGY (2018)
Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis
Mariana Pavel et al.
NATURE COMMUNICATIONS (2018)
mTOR signalling and cellular metabolism are mutual determinants in cancer
Dirk Mossmann et al.
NATURE REVIEWS CANCER (2018)
Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer
Pranavi Koppula et al.
CANCER COMMUNICATIONS (2018)
MG132 plus apoptosis antigen-1 (APO-1) antibody cooperate to restore p53 activity inducing autophagy and p53-dependent apoptosis in HPV16 E6-expressing keratinocytes
Alfredo Lagunas-Martinez et al.
APOPTOSIS (2017)
Reactive oxygen species and cancer paradox: To promote or to suppress?
Sehamuddin Galadari et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate
Pranavi Koppula et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation
Takeo Goji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
Yuchao Gu et al.
MOLECULAR CELL (2017)
Hippo pathway mediates resistance to cytotoxic drugs
Taranjit S. Gujral et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT
Evan C. Lien et al.
SCIENCE SIGNALING (2017)
The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility
Chun-Shik Shin et al.
NATURE COMMUNICATIONS (2017)
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT
Evan C. Lien et al.
SCIENCE SIGNALING (2017)
Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy
Chang Hoon Ji et al.
MOLECULES AND CELLS (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-)
Kenji Tsuchihashi et al.
CANCER RESEARCH (2016)
An evolutionarily conserved pathway controls proteasome homeostasis
Adrien Rousseau et al.
NATURE (2016)
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
Nissim Hay
NATURE REVIEWS CANCER (2016)
Ferroptosis as a p53-mediated activity during tumour suppression
Le Jiang et al.
NATURE (2015)
mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
Jinghui Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Inhibition of the MDM2 E3 Ligase Induces Apoptosis and Autophagy in Wild-Type and Mutant p53 Models of Multiple Myeloma, and Acts Synergistically with ABT-737
Dongmin Gu et al.
PLOS ONE (2014)
Contact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence program
Olga V. Leontieva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The Cystine/Glutamate Antiporter System xc- in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
Jan Lewerenz et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
A novel crosstalk between two major protein degradation systems Regulation of proteasomal activity by autophagy
Xiao J. Wang et al.
AUTOPHAGY (2013)
mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State
Chunlei Cang et al.
CELL (2013)
The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl
N. Reuven et al.
CELL DEATH AND DIFFERENTIATION (2013)
Increased xCT Expression Correlates With Tumor Invasion and Outcome in Patients With Glioblastomas
Satoru Takeuchi et al.
NEUROSURGERY (2013)
The oxidative stress-inducible cystine/glutamate antiporter, system xc-: cystine supplier and beyond
Marcus Conrad et al.
AMINO ACIDS (2012)
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Patrick S. Ward et al.
CANCER CELL (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
Carmine Settembre et al.
EMBO JOURNAL (2012)
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
Agnes Roczniak-Ferguson et al.
SCIENCE SIGNALING (2012)
CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc- and Thereby Promotes Tumor Growth
Takatsugu Ishimoto et al.
CANCER CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins
Gen Matsumoto et al.
MOLECULAR CELL (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
mTOR regulation of autophagy
Chang Hwa Jung et al.
FEBS LETTERS (2010)
Inhibition of lysosomal functions reduces proteasomal activity
Liyan Qiao et al.
NEUROSCIENCE LETTERS (2009)
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello et al.
SCIENCE (2009)
Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells
M. A. Westhoff et al.
ONCOGENE (2008)
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2007)
Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes
Ephraim Fass et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Hypoxia-induced energy stress regulates mRNA translation and cell growth
LP Liu et al.
MOLECULAR CELL (2006)
TSC2 mediates cellular energy response to control cell growth and survival
K Inoki et al.
CELL (2003)
Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
SA Mousavi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2001)