4.4 Article

Anti-inflammatory active components of the roots of Datura metel

Journal

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 23, Issue 4, Pages 392-398

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2020.1739660

Keywords

Solanaceae; Datura metel; phenolic glycoside; anti-inflammatory activity

Funding

  1. Guidance Plan of Science and Technology Research and Development of Shijiazhuang [171461533]

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A new phenolic glycoside, along with 10 known compounds, were isolated from the roots of Datura metel. The structures of these compounds were identified based on spectroscopic data, and their in vitro anti-inflammatory activities were evaluated.
One new phenolic glycoside, methyl 3,4-dihydroxyphenylacetate-4-O-[2-O-beta-D-apisoyl-6-O-(2-hydroxybenzoyl)]-beta-D-glucopyranoside (1), together with 10 known compounds (2-11), were isolated from the roots of Datura metel. The structures of these compounds were elucidated on the basis of their spectroscopic data. Furthermore, the in vitro anti-inflammatory activities of compounds 1-11 were evaluated.

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