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Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice
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EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in mice
Jugta Khuman et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)
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Luca Longhi et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2011)
Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment
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Omega-3 fatty acid supplementation and reduction of traumatic axonal injury in a rodent head injury model Laboratory investigation
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JOURNAL OF NEUROSURGERY (2011)
Rotational Acceleration Closed Head Flexion Trauma Generates More Extensive Diffuse Brain Injury than Extension Trauma
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Severity Profile of Penetrating Ballistic-Like Brain Injury on Neurofunctional Outcome, Blood-Brain Barrier Permeability, and Brain Edema Formation
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JOURNAL OF NEUROTRAUMA (2011)
Minocycline Restores sAPPα Levels and Reduces the Late Histopathological Consequences of Traumatic Brain Injury in Mice
Eleni Siopi et al.
JOURNAL OF NEUROTRAUMA (2011)
IL6 Deficiency Affects Function After Traumatic Brain Injury
Eric J. Ley et al.
JOURNAL OF SURGICAL RESEARCH (2011)
Population-Based Study of the Risk of In-Hospital Death After Traumatic Brain Injury: The Role of Sepsis
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Immune cell regulation by autocrine purinergic signalling
Wolfgang G. Junger
NATURE REVIEWS IMMUNOLOGY (2011)
Overview of the immune response
David D. Chaplin
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2-/- mice
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JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2010)
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Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury
Louis J. Sparvero et al.
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Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients
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Genetic Analysis of the Role of Tumor Necrosis Factor Receptors in Functional Outcome after Traumatic Brain Injury in Mice
Jinsheng Yang et al.
JOURNAL OF NEUROTRAUMA (2010)
Blockade of Acute Microglial Activation by Minocycline Promotes Neuroprotection and Reduces Locomotor Hyperactivity after Closed Head Injury in Mice: A Twelve-Week Follow-Up Study
Shadi Homsi et al.
JOURNAL OF NEUROTRAUMA (2010)
Fluid-percussion-induced traumatic brain injury model in rats
Shruti V. Kabadi et al.
NATURE PROTOCOLS (2010)
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Victoria E. Johnson et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration and cortical damage following closed head injury
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NEUROBIOLOGY OF DISEASE (2010)
Involvement of Pro- and Anti-Inflammatory Cytokines and Chemokines in the Pathophysiology of Traumatic Brain Injury
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Antioxidant Therapies for Traumatic Brain Injury
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NEUROTHERAPEUTICS (2010)
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SCIENCE (2010)
Atorvastatin ameliorates cerebral vasospasm and early brain injury after subarachnoid hemorrhage and inhibits caspase-dependent apoptosis pathway
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BMC NEUROSCIENCE (2009)
Time course of hippocampal IL-1 β and memory consolidation impairments in aging rats following peripheral infection
Ruth M. Barrientos et al.
BRAIN BEHAVIOR AND IMMUNITY (2009)
Minocycline effects on cerebral edema: Relations with inflammatory and oxidative stress markers following traumatic brain injury in mice
Shadi Homsi et al.
BRAIN RESEARCH (2009)
C1-inhibitor attenuates neurobehavioral deficits and reduces contusion volume after controlled cortical impact brain injury in mice
Luca Longhi et al.
CRITICAL CARE MEDICINE (2009)
Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice
Fredrik Clausen et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Simvastatin reduces secondary brain injury caused by cortical contusion in rats: Possible involvement of TLR4/NF-κB pathway
Gang Chen et al.
EXPERIMENTAL NEUROLOGY (2009)
Systemic inflammatory response following acute traumatic brain injury
Jia Lu
Frontiers in Bioscience-Landmark (2009)
Activation of Metabotropic Glutamate Receptor 5 Modulates Microglial Reactivity and Neurotoxicity by Inhibiting NADPH Oxidase
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The role of the choroid plexus in neutrophil invasion after traumatic brain injury
Joanna Szmydynger-Chodobska et al.
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Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury
Juan Pablo de Rivero Vaccari et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2009)
Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice
Philip F. Stahel et al.
JOURNAL OF NEUROINFLAMMATION (2009)
NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats
Hans H. Wei et al.
JOURNAL OF NEUROINFLAMMATION (2009)
Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury
Ann C. McKee et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Depletion of Ly6G/Gr-1 Leukocytes after Spinal Cord Injury in Mice Alters Wound Healing and Worsens Neurological Outcome
David P. Stirling et al.
JOURNAL OF NEUROSCIENCE (2009)
Repeated Traumatic Brain Injury Affects Composite Cognitive Function in Piglets
Stuart H. Friess et al.
JOURNAL OF NEUROTRAUMA (2009)
Blast Overpressure in Rats: Recreating a Battlefield Injury in the Laboratory
Joseph B. Long et al.
JOURNAL OF NEUROTRAUMA (2009)
Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury
David J. Loane et al.
NATURE MEDICINE (2009)
CONCUSSION IN PROFESSIONAL FOOTBALL: ANIMAL MODEL OF BRAIN INJURY-PART 15
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NEUROSURGERY (2009)
Atorvastatin efficiency after traumatic brain injury in rats
Omer Faruk Turkoglu et al.
SURGICAL NEUROLOGY (2009)
Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice
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PLOS MEDICINE (2009)
Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
Jing Chen et al.
BRAIN BEHAVIOR AND IMMUNITY (2008)
Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury
Rajat Sandhir et al.
EXPERIMENTAL NEUROLOGY (2008)
Effect of rosuvastatin on amnesia and disorientation after traumatic brain injury (NCT003229758)
J. Humberto Tapia-Perez et al.
JOURNAL OF NEUROTRAUMA (2008)
Moderate and severe traumatic brain injury in adults
Andrew I. R. Maas et al.
LANCET NEUROLOGY (2008)
HMGB1: Endogenous danger signaling
John R. Klune et al.
MOLECULAR MEDICINE (2008)
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
Charles N. Serhan et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system
Jonathan P. Godbout et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4
Zerong You et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice
Daniela Bermpohl et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Diffuse brain injury in the immature rat: Evidence for an age-at-injury effect on cognitive function and histopathologic damage
Ramesh Raghupathi et al.
JOURNAL OF NEUROTRAUMA (2007)
New rat model for diffuse brain injury using coronal plane angular acceleration
Ronald J. Fijalkowski et al.
JOURNAL OF NEUROTRAUMA (2007)
T lymphocyte trafficking: A novel target for neuroprotection in traumatic brain injury
Fredrik Clausen et al.
JOURNAL OF NEUROTRAUMA (2007)
Lovastatin improves histological and functional outcomes and reduces inflammation after experimental traumatic brain injury
Szu-Fu Chen et al.
LIFE SCIENCES (2007)
Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat
Anthony J. Williams et al.
JOURNAL OF NEUROINFLAMMATION (2007)
Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury
Haichen Wang et al.
EXPERIMENTAL NEUROLOGY (2007)
Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice
Iris Leinhase et al.
JOURNAL OF NEUROINFLAMMATION (2007)
Systemic infections and inflammation affect chronic neurodegeneration
V. Hugh Perry et al.
NATURE REVIEWS IMMUNOLOGY (2007)
DAMPs, PAMPs and alarmins: all we need to know about danger
Marco E. Bianchi
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Repetitive mild non-contusive brain trauma in immature rats exacerbates traumatic axonal injury and axonal calpain activation: A preliminary report
Jimmy W. Huh et al.
JOURNAL OF NEUROTRAUMA (2007)
Resolvins and protectins in the termination program of acute inflammation
Amirarn Ariel et al.
TRENDS IN IMMUNOLOGY (2007)
Severity level and injury track determine outcome following a penetrating ballistic-like brain injury in the rat
Anthony J. Williams et al.
NEUROSCIENCE LETTERS (2006)
Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination
Chao Zhao et al.
NEUROBIOLOGY OF AGING (2006)
Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation
Iris Leinhase et al.
BMC NEUROSCIENCE (2006)
n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases
Philip C. Calder
AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)
Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury
Iris Leinhase et al.
EXPERIMENTAL NEUROLOGY (2006)
mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging
MG Frank et al.
NEUROBIOLOGY OF AGING (2006)
Clinical features of fever associated with poor outcome in severe pediatric traumatic brain injury
P Suz et al.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY (2006)
Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration
C Cunningham et al.
JOURNAL OF NEUROSCIENCE (2005)
Effects of atorvastatin on spatial memory, neuronal survival, and vascular density in female rats after traumatic brain injury
CS Qu et al.
JOURNAL OF NEUROSURGERY (2005)
Concomitant upregulation of nuclear factor-κB activity, proinflammatory cytokines and ICAM-1 in the injured brain after cortical contusion trauma in a rat model
CH Hang et al.
NEUROLOGY INDIA (2005)
Antagonism of the interleukin-1 receptor following traumatic brain injury in the mouse reduces the number of nitric oxide synthase-2-positive cells and improves anatomical and functional outcomes
NC Jones et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Pathophysiology of polytrauma
M Keel et al.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2005)
Cerebrospinal fluid concentrations of anti-inflammatory mediators in early-phase severe traumatic brain injury
T Shiozaki et al.
SHOCK (2005)
Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system
JP Godbout et al.
FASEB JOURNAL (2005)
Characterization of a new rat model of penetrating ballistic brain injury
AJ Williams et al.
JOURNAL OF NEUROTRAUMA (2005)
Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in mice: More than a focal brain injury
ED Hall et al.
JOURNAL OF NEUROTRAUMA (2005)
Traumatic axonal injury is exacerbated, following repetitive closed head injury in the neonatal pig
R Raghupathi et al.
JOURNAL OF NEUROTRAUMA (2004)
The pathobiology of moderate diffuse traumatic brain injury as identified using a new experimental model of injury in rats
I Cernak et al.
NEUROBIOLOGY OF DISEASE (2004)
Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury
T Hayakata et al.
SHOCK (2004)
Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury
DY Lu et al.
JOURNAL OF NEUROTRAUMA (2004)
Atorvastatin reduction of intravascular thrombosis, increase in cerebral microvascular patency and integrity, and enhancement of spatial learning in rats subjected to traumatic brain injury
DY Lu et al.
JOURNAL OF NEUROSURGERY (2004)
Atorvastatin reduction of intracranial hematoma volume in rats subjected to controlled cortical impact
DY Lu et al.
JOURNAL OF NEUROSURGERY (2004)
Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial):: randomised placebo-controlled trial
I Muzha et al.
LANCET (2004)
Free fatty acids in cerebrospinal fluids from patients with traumatic brain injury
JG Pilitsis et al.
NEUROSCIENCE LETTERS (2003)
Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury
M Penkowa et al.
EXPERIMENTAL NEUROLOGY (2003)
Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury
I Yatsiv et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
The inflammasome:: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
F Martinon et al.
MOLECULAR CELL (2002)
CD14 expression by activated parenchymal microglia/macrophages and infiltrating monocytes following human traumatic brain injury
R Beschorner et al.
ACTA NEUROPATHOLOGICA (2002)
HSP70 protects against TNF-induced lethal inflammatory shock
W Van Molle et al.
IMMUNITY (2002)
Repetitive mild brain trauma accelerates Aβ deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis
K Uryu et al.
JOURNAL OF NEUROSCIENCE (2002)
The systemic and local acute phase response following acute brain injury
DC Wilcockson et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
Mild head injury increasing the brain's vulnerability to a second concussive impact
HL Laurer et al.
JOURNAL OF NEUROSURGERY (2001)
Intrathecal levels of complement-derived soluble membrane attack complex (sC5b-9) correlate with blood-brain barrier dysfunction in patients with traumatic brain injury
PF Stahel et al.
JOURNAL OF NEUROTRAUMA (2001)
Markers for cell-mediated immune response are elevated in cerebrospinal fluid and serum after severe traumatic brain injury in humans
PM Lenzlinger et al.
JOURNAL OF NEUROTRAUMA (2001)
Brain dendritic cells and macrophages/microglia in central nervous system inflammation
HG Fischer et al.
JOURNAL OF IMMUNOLOGY (2001)
Effect of neutropenia and granulocyte colony stimulating factor-induced neutrophilia on blood-brain barrier permeability and brain edema after traumatic brain injury in rats
MJ Whalen et al.
CRITICAL CARE MEDICINE (2000)